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Wednesday, March 27, 2013

Mammary gland morphology and gene expression differ in female rats treated with 17β-estradiol or fed soy protein isolate

Posted by Chantel M. research contributed  US National Library of Medicine National Institutes of Health 
Soy foods have been suggested to have both positive health benefits and potentially adverse effects as a result of their content of phytoestrogens.  In the study to compare the effects of soy protein isolate (SPI), the protein in soy infant formula, with those of 17β-estradiol (E2), on global gene expression profiles and morphology in the female rat mammary gland, with rats fed AIN-93G diets containing casein or SPI beginning on postnatal d 30, posted in PubMed, searchers found that SPI is only minimally estrogenic in the rat mammary gland even in the absence of endogenous estrogens.

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