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Saturday, February 22, 2014

Olive Oil and Endometrial Cancer

 Posted by Chantel Martiromo

The incidence of endometrial cancer among white women are higher in comparison of black women. According to the statistic, the risk of endometrial cancer among women is 1 in 7000. Every year, about 40,000 women in US are diagnosed with the disease. Women who carry certain mutation genes, such as  BRCA1 or the BRCA2 are associated to increased risk of endometrial cancer.
Endometrium is the inner lining of the mammalian uterus and very susceptible hormone change, particular to menstrual cycle. Endometrial cancer is a late adulthood cancer defined as a condition of which the cells of the endometrial lining of uterus have growth uncontrollable or become cancerous as a result of the alternation of cells DNA. It's the fourth most common cancer among women overall, after breast cancer, lung cancer, and bowel cancer.
Olive is belongs to the the family Oleaceae, native to the coastal areas of the eastern Mediterranean Basin and south end of the Caspian Sea. Its fruit, is also called the olive and the source of olive oil.
According to the study by the University of Athens Medical School, increased intake of monounsaturated fat, mostly olive oil, was associated with endometrial cancer risk reduction and increase olive oil intake by 1 standard deviation, risk of endometrial cancer reduced by 26% (34). In a 84 women study with intact uterus admitted to the same teaching hospital in Athens, showed that risk of endometrial cancer is reduced with intake Retinol, nicotinic acid, vitamin B- 6, and riboflavin, but olive oil was highly suggestive(35). Other researchers suggested since the incidence of cancer overall in Mediterranean countries is lower than in Scandinavian countries, the United Kingdom, and the United States, it may be result of healthy traditional Mediterranean diet(36).

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(34) Dietary factors and the risk of endometrial cancer: a case--control study in Greece by Tzonou A1, Lipworth L, Kalandidi A, Trichopoulou A, Gamatsi I, Hsieh CC, Notara V, Trichopoulos D(PubMed)
(35) Diet in relation to endometrial cancer risk: a case-control study in Greece by Petridou E1, Kedikoglou S, Koukoulomatis P, Dessypris N, Trichopoulos D(PubMed)
(36) Cancer and Mediterranean dietary traditions by Trichopoulou A1, Lagiou P, Kuper H, Trichopoulos D.(PubMed)

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