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Wednesday, March 26, 2014

Ovarian Cancer and Rice bran

 Posted by Chantel Martiromo

Ovarian cancer is defined as a condition of  abnormal ovarian cells growth of ovaries.  It is one of most common cancer in US, according to the statistics adapted from the American Cancer Society's publication, Cancer Facts & Figures 2010, an estimated 21,880 women in the United States were diagnosed with ovarian cancer, causing 3,850 deaths.
Rice bran
Rice bran contains layer between the inner white rice grain and the outer hull. Phytic acid (PA) isolated from rice bran induced marked growth inhibition in ovary, with 50% growth inhibition concentration (IC50)(30). In methanolic extracts from Njavara rice bran, showed to exhibit its anti-proliferative property in C6 glioma cells, possibly through superior antioxidant activity as evidenced by scavenging of free radicals including DPPH and NO(31).
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(30) Antioxidant and cytotoxicity effect of rice bran phytic acid as an anticancer agent on ovarian, breast and liver cancer cell lines by Norhaizan ME1, Ng SK, Norashareena MS, Abdah MA.(PubMed)
(31) The antioxidant and antiproliferative activities of methanolic extracts from Njavara rice bran by Rao AS1, Reddy SG, Babu PP, Reddy AR.(PubMed)

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