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Thursday, April 21, 2016

The Best Smoothie of Grape, Turmeric and Green Tea for Prevention and Treatment of Hemochromatosis

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of  Hemochromatosis
Yield: 2 servings (about 8 ounces each)
1 1/2 cups grape
1 tsp Turmeric powder
1 cup green tea drink (Make from 4 grams of green tea and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of   Hemochromatosis has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Hemochromatosis is a hereditary disorder with iron salts deposited in the tissues, leaded to liver damage, diabetes mellitus, and bronze discoloration of the skin.

Recent studies back by well known institutions proposed, Grape, Turmeric and  Green Tea may be the next generation of natural ingredients for prevention and treatment of Gilbert’s Syndrome. Dr. Isa HM and Dr. Mohamed AM. said, "Neonatal hemochromatosis is a rare liver disease of newborns with a spectrum of clinical severity......The use of antioxidant therapy helps to improve the outcome"(3).

Resveratrol, phytochemical in the class of Stilbenoids, found abundantly in blueberry and grape inhibited abnormal iron metabolism and directly protected the liver from iron-mediated injury through its pleotropic antioxidant properties(1).
According to joint study lead by the University of Alberta, resveratrol ameliorated the burden from iron-overload cardiomyopathy at early and chronic stages of iron-overload(2).

Silybin, an antioxidant found abundantly in Turmeric, a yellow powder and used as a spice in curry dishes may be beneficiary for patient with Hemochromatosis. According to King's College London, silybin reduced iron absorption in patients with hereditary haemochromatosis through reduction in the postprandial increase in serum iron (AUC±s.e.)(4).

Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. According to the der Johann Wolfgang Goethe-Universit├Ąt, regular tea drinking with meals reduces the frequency of phlebotomies required in the management of patients with haemochromatosis. due to its inhibition of intestinal absorption of non-haem iron(5).

Dr. Borch-Iohnsen B, in the study of Primary haemochromatosis diet said," (regular) tea or coffee with meals will reduce iron absorption"(6).

Taking altogether, the combination of Grape, Turmeric and Green Tea may process the activities in reduced risk and treatment of patient with Hemochromatosis.

People with gene mutation of  Hemochromatosis due to family history, genetic mutation, .... should drink 1 serving daily and people with Hemochromatosis induced live disease should drink as much as they can, depending to digestive toleration.
Life style and diet pattern changed are recommended

(1) Resveratrol mediates therapeutic hepatic effects in acquired and genetic murine models of iron-overload by Das SK1, DesAulniers J1, Dyck JR2, Kassiri Z3, Oudit GY1,3.(PubMed)
(2) Iron-overload injury and cardiomyopathy in acquired and genetic models is attenuated by resveratrol therapy by Das SK1,2, Wang W2,3, Zhabyeyev P1,2, Basu R1,2, McLean B2,3, Fan D2,3, Parajuli N1,2, DesAulniers J1,2, Patel VB1,2, Hajjar RJ4, Dyck JR5, Kassiri Z2,3,Oudit GY1,2.(PubMed)
(3) Neonatal hemochromatosis. Case series from Bahrain by Isa HM1, Mohamed AM.(PubMed)
(4) The iron-chelating potential of silybin in patients with hereditary haemochromatosis. by Hutchinson C1, Bomford A, Geissler CA.(PubMed)
(5) Clinical trial on the effect of regular tea drinking on iron accumulation in genetic haemochromatosis by Kaltwasser JP1, Werner E, Schalk K, Hansen C, Gottschalk R, Seidl C.(PubMed)
(6) [Primary hemochromatosis and dietary iron].[Article in Norwegian] by Borch-Iohnsen B1.(PubMed)

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