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Thursday, April 28, 2016

Women Health: The Smoothie of Unripe whole foods papaya and Fortified Low Fat Milk For Gestational Diabetes

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for reduced risk and treatment of Gestational Diabetes
Yield: 3 serving (about 8 ounce each)
1 1/2 cup unripe whole food Papaya
1 cup of fortified vitamin D low fat milk

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for reduced risk and treatment of pospartum depression has encountered many obstacles, many ingredients showed initially the promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Scientists in some well known institutions may have found the therapeutic and potential ingredients from natural sources(Green tea and grape) for reduced risk and treatment of pospartum depression.
Diabetes is a condition caused by insufficient insulin entering the bloodstream to regulate the glucose. It is either caused by cells in pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.

Women who are diagnosed with gestational Diabetes should pay attention to preconception care recommended by the Society of Obstetricians and Gynaecologists of Canada (SOGC).
According to the joint study led by the Wollongong Hospital, Wollongong, the prevalence of hyperglycaemia in pregnancy (HIP) was 13.1% with diabetes mellitus in pregnancy (DIP) being 0.4% and gestational diabetes mellitus (GDM) being 12.7% in Australia(1).

According to the joint study led by the Wollongong Hospital, Wollongong, the prevalence of hyperglycaemia in pregnancy (HIP) was 13.1% with diabetes mellitus in pregnancy (DIP) being 0.4% and gestational diabetes mellitus (GDM) being 12.7% in Australia(1).

Women with Type II Diabetes during pregnancy may also be thinking to add whole food papaya into their diet. the recent study suggested(7) ,
The finding not only showed the effectiveness of unripe pawpaw fruit (Carica papaya) in inhibition α-amylase, α-glucosidase, but also induced lipid peroxidation in a dose-dependent manner, in rat pancreas(2).

The key enzymes of α-amylase, α-glucosidase, involved in the digestion of carbohydrates, have been linked to onset of type 2 diabetes. Inhibition of these enzymes can significantly reduce the post-prandial increase of blood glucose and have been considered by therapists in use for management of blood glucose level in type 2 diabetic and borderline patients(3).

In streptozotocin-induced diabetic rats study, the aqueous extract of leaves of C. papaya administered strongly controlled blood glucose levels(9), through prevention of hepatocyte disruption, as well as accumulation of glycogen and lipids via its hypoglycemic and antioxidant effect(4)

In a new study, conducted by the researchers at the Davis Heart and Lung Research Institute, fermented papaya preparation was tested whether it improves dermal wound healing outcomes in adult diabetic mice by preventing the risk of infections(5).
The result was astonishing, the fermentation not only up regulated the Sp1 DNA binding activity(modulating the cellular response to DNA damage) in Peripheral blood mononuclear cells (PBMC) but also the protein and mRNA expression of Rac2(regulates a number of cellular functions)(6).

A randomized controlled clinical trial conducted at the Cardiac Centre, ANDI Centre of Excellence for Biomedical and Biomaterials Research and Department of Biosciences University of Mauritius, suggested that oral administration of 6g FPP®/day for a period of 14 weeks could improve the general health status of several organs targeted by oxidative stress duringdiabetes and suggested that the supplement may be used in the management the complications of diabetes such as cardiovascular disease, neurological disease and other conditions worsened by overt inflammation and oxidative stress(7).

Women with Gestational Diabetes should drink 4 servings daily depending to digestive toleration.
Change life style and diet pattern are also recommended.

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(1) The prevalence of hyperglycaemia in pregnancy in Australia by Moses RG1, Wong VC1, Lambert K1, Morris GJ2, San Gil F1.(PubMed)
(2) Inhibition of key enzymes linked to type 2 diabetes and sodium nitroprusside-induced lipid peroxidation in rat pancreas by water-extractable phytochemicals from unripe pawpaw fruit (Carica papaya) by Oboh G, Olabiyi AA, Akinyemi AJ, Ademiluyi AO.(PubMed)
(3) Natural products as alpha-amylase and alpha-glucosidase inhibitors and their hypoglycaemic potential in the treatment of diabetes: an update by Tundis R1, Loizzo MR, Menichini F.(PubMed)
(4) Antihyperglycemic and hypolipidemic activities of aqueous extract ofCarica papaya Linn. leaves in alloxan-induced diabetic rats by Maniyar Y, Bhixavatimath P.(PubMed)
(5) Hypoglycemic effect of Carica papaya leaves in streptozotocin-induced diabetic rats by Juárez-Rojop IE1, Díaz-Zagoya JC, Ble-Castillo JL, Miranda-Osorio PH, Castell-Rodríguez AE, Tovilla-Zárate CA, Rodríguez-Hernández A, Aguilar-Mariscal H, Ramón-Frías T, Bermúdez-Ocaña DY.(PubMed)
(6) Correction of aberrant NADPH oxidase activity in blood-derived mononuclear cells from type II diabetes mellitus patients by a naturally fermented papaya preparation by Dickerson R1, Deshpande B, Gnyawali U, Lynch D, Gordillo GM, Schuster D, Osei K, Roy S.(PubMed)
(7) Effects of a short term supplementation of a fermented papaya preparation on biomarkers of diabetes mellitus in a randomized Mauritian population by Somanah J1, Aruoma OI, Gunness TK, Kowelssur S, Dambala V, Murad F, Googoolye K, Daus D, Indelicato J, Bourdon E, Bahorun T.(PubMed)

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