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Monday, April 18, 2016

Women Health: The Best Cabbage, Flax Seed and Panax Ginseng Powder for Prevention and Treatment of Urogenital atrophy

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The Incredible and Effective smoothie for Reduced Risk and Treatment of Urogenital atrophy
Yield: 2 servings (about 8 ounces each)
1   cup cabbage for t
1/4 cup flax seed
1/4 cup honey for tast
1 cup Panax ginseng drink (Make from 2 grams of Panax ginseng powder and a cup of hot water lipped for 5 minutes, and let cool to room temperature)
1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

Urogenital atrophy is a condition of changes in the vagina and urethra due to declining estrogen levels in these tissues.

The finding of a natural source for reduced risk and treatment of Urogenital atrophy to replace the oral hormone replacement therapy (HRT), has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in either large sample size and mutli centers human trials.

Strong evidences of number of renowned institutions suggested that natural sources, such as Isoflavones found in legume, serotonin found in flax seed processed alleviating vasomotor episodes, attenuating bone loss, and stimulating vaginal epithelial maturation,. according to the joint study lead by The Chiang Mai University(1).

Dr.Sobenin IA and researcher at the Russian Cardiology Research and Production Complex, said, "Phytoestrogens are often considered as a possible alternative to hormone replacement therapy, since they are believed to alleviate some symptoms of menopause, such as, therosclerosis and atherosclerosis-related diseases through multiple mechanisms"(2).
In Fact, Phytoestrogens can play an important role in symptoms of menopause including fatigue, insomnia, problems with concentrations and depression symptoms and on women organism during menopausal period(3).

Levels of serotonin found abundantly in flax seed, is associated to reduced risk, frequency and severity of vasomotor symptoms in menopausal women(4). According to the Massachusetts General Hospital, serotonin-norepinephrine reuptake inhibitor duloxetine significant improve dpression, vasomotor symptoms, sleep, anxiety, and pain after 8 weeks(5).

Dr. Joffe H and the research team at the joint study lead Harvard Medical School, low-dose oral estradiol and venlafaxine(serotonin-norepinephrine reuptake inhibitor ) are effective treatments for VMS in women during midlife(6).

Another selective serotonin reuptake inhibitor, escitalopram, also alleviated the frequency, severity, and bother of menopausal hot flashes in the study of 205 women (95 African American; 102 white; 8 other) between July 2009 and June 2010.(7).

Ginseng is a slow-growing perennial plants with fleshy roots, the genus Panax, belongings to the family Araliaceae. Depending to the climate where it grows, ginseng can be classified mainly into Panax ginseng Asian ginseng (root), Red ginseng, wild ginseng, American ginseng (root). The herb(Panax ginseng) may be used for treatment of reduced estrogen levels due to aging in women becaused of its ginsenoside Rb in exhibited phytoestrogen like effects(8).
According to the China Pharmaceutical University in ovariectomized mice study suggested that ginsenoside Rb1 (Rb1) isolated from Panax ginseng, increased 5-hydroxytryptamine (5-HT) concentration via its estrogen-like effect(9).

The effectiveness of Cabbage, Flax Seed and Panax Ginseng Powder may serve as cornerstones of pharmaceutical target for further studies in production of a potential medication for for Reduced Risk of Consequences of  Urogenital atrophy with little or no adverse effects.

Women who are pregnancy may want to stop drinking excessively. Otherwise, intake of
Smoothie of Cabbage, Flax Seed and Panax Ginseng Powde may Reduced Risk and treatment of Urogenital atrophy.
Life style and dietary patter change are recommended.

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(1) Open, non-controlled clinical studies to assess the efficacy and safety of a medical device in form of gel topically and intravaginally used in postmenopausal women with genital atrophy by Morali G1, Polatti F, Metelitsa EN, Mascarucci P, Magnani P, Marrè GB.(PubMed)
(2) Phytoestrogen-Rich Dietary Supplements in Anti-Atherosclerotic Therapy in Postmenopausal Women by Sobenin IA1, Myasoedova VA, Orekhov AN.(PubMed)
(3) [Phytoestrogens--whether can they be an alternative to hormone replacement therapy for women during menopause period?].[Article in Polish] by Dittfeld A, Koszowska A, Brończyk AP, Nowak J, Gwizdek K, Zubelewicz-Szkodzińska B.(PubMed)
(4) Methods for the design of vasomotor symptom trials: the menopausal strategies: finding lasting answers to symptoms and health network by Newton KM1, Carpenter JS, Guthrie KA, Anderson GL, Caan B, Cohen LS, Ensrud KE, Freeman EW, Joffe H, Sternfeld B, Reed SD,Sherman S, Sammel MD, Kroenke K, Larson JC, Lacroix AZ.(PubMed)
(5) Treatment of depression and menopause-related symptoms with the serotonin-norepinephrine reuptake inhibitor duloxetine. by Joffe H1, Soares CN, Petrillo LF, Viguera AC, Somley BL, Koch JK, Cohen LS.(PubMed)
(6) Low-dose estradiol and the serotonin-norepinephrine reuptake inhibitor venlafaxine forvasomotor symptoms: a randomized clinical trial by Joffe H1, Guthrie KA2, LaCroix AZ2, Reed SD3, Ensrud KE4, Manson JE5, Newton KM6, Freeman EW7, Anderson GL2, Larson JC2, Hunt J2,Shifren J8, Rexrode KM5, Caan B9, Sternfeld B9, Carpenter JS10, Cohen L8(PubMed)
(7) Efficacy of escitalopram for hot flashes in healthy menopausal women: a randomized controlled trial. by Freeman EW1, Guthrie KA, Caan B, Sternfeld B, Cohen LS, Joffe H, Carpenter JS, Anderson GL, Larson JC, Ensrud KE, Reed SD, Newton KM, Sherman S, Sammel MD, LaCroix AZ.(PubMed)
(8) Beneficial estrogen-like effects of ginsenoside Rb1, an active component of Panax ginseng, on neural 5-HT disposition and behavioral tasks in ovariectomized mice by Hao K1, Gong P1, Sun SQ1, Hao HP1, Wang GJ1, Dai Y2, Liang Y1, Xie L1, Li FY1.(PubMed)
(9) Mechanism-based pharmacokinetic-pharmacodynamic modeling of the estrogen-like effect of ginsenoside Rb1 on neural 5-HT in ovariectomized mice by Hao K1, Gong P, Sun SQ, Hao HP, Wang GJ, Dai Y, Chen YC, Liang Y, Xie L, Li FY, Li HY.(PubMed)

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