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Monday, April 25, 2016

Women Health: The Smoothie of Carrot, Brazil Nut and Green Tea for Prevention and Treatment of Vulvar Cancer

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

The smoothie for prevention and treatment of  Vulvar Cancer
Yield: 2 servings (about 8 ounces each)
1 cup Brazil nut
1/2 cup carrot
1 cup green tea drink (Make from 4 grams of green tea and a cup of hot water lipped for 5 minutes, and let cool to room temperature)

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed.
3. Serve immediately

The finding of a natural source for treatment of  Vulvar Cancer has been running into many obstacles, many ingredients showed initially with promising result in animal studies have not produced same potentials in large sample size and mutli centers human trials.

Vulva cancer is a cancer arises from the abnormal cells growth of the epidermis of the vulvar tissue. The invasive cancer tends to affects women in later life and accounts for approximate 4 % of all female reproductive organs cancers.
Recent studies back by well known institutions proposed, Green Tea(1) may be the next generation of natural ingredients for prevention and treatment of Vulvar Cancer.
Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Due to its commercial values and health effects, green tea now has been cultivated all over the world in suitable climate. According to Associates in Women's Health Care, women who adopt healthy lifestyles and practice preventive healthy behaviors can reduce the risks of some cancers and other diseases, such as drinking tea(1) and intake of tomatoes regularly(1) and  Pap smear in screening(1)(2).
Dr. Han J said,"green tea extract inhibited 12-O-tetradecanoylphorbol-3-acetate-induced epidermal ornithine decarboxylase activity and counteracted 12-O-tetradecanoylphorbol-3-acetate-induced ear edema in mice. It is interesting that green tea extract inhibited the transformation of Balb/c 3T3 cells induced by methylcholanthrene and 12-O-tetradenanoylphorbol-3-acetate" of that related to the develop and progression of vulvar leukoplakia(3).

Major carotenoids, particular alpha carotene in common fruits and vegetables such as tomatoes and carrot might have a protective and preventive effect in reduced risk of Vulvar Cancer(4). According to the study of a total of in 88 women with gynecologic cancer (9vulvar, 15 cervical, 36 endometrial and 28 ovarian carcinomas) and 31 healthy control by Tampere University Central Hospital, serum of vitamin A is lower in women with vulvar Cancer(5).
13-cis-retinoic acid, a synthetic version with similar effect as vitamin A showed a significant effect in chronic epithelial vulvar dystrophies from long term and local retinoid treatment(6). The chemical also induced complete disappearance of dystrophy of the vulva in 33 out of 53 patients(7).

Selenium found abundantly in Brazil nut may also exhibited anti cancer effect(3). Patients with vulvar cancer are associated to reduced serum of selenium and antioxidative mechanisms(8).
Dr, Sundström H and colleagues,said," (selenium ) may be defective and that treatment with selenium and vitamin E results in changes of biochemical factors related to lipid peroxidation (in in uterine, ovarian or vulvar cancer)"(8).

Taking altogether, the combination of Carrot, Brazil Nut and Green Tea may process the activities in reduced risk and treatment of patient with Vulvar Cancer
Women who are at increased risk of Vulvar Cancer due to family history, genetic mutation, .... should drink 1 serving daily and people with Vulvar Cancer should drink as much as they can, depending to digestive toleration.
Life style and diet pattern changed are recommended

(1) Tomatoes, Pap smears, and tea? Adopting behaviors that may prevent reproductive cancers and improve health by Furniss K1.(PubMed)
(2) Screening for gynecologic cancer. Vulvar, vaginal, endometrial, and ovarian neoplasms by Hall KL1, Dewar MA, Perchalski J.(PubMed)
(3) Highlights of the cancer chemoprevention studies in China by Han J1.(PubMed)
(4) Diet and the risk of vulvar cancer by Sturgeon SR1, Ziegler RG, Brinton LA, Nasca PC, Mallin K, Gridley G.(PubMed)
(5) Serum vitamins A and E and carotene in patients with gynecologic cancer by Heinonen PK1, Kuoppala T, Koskinen T, Punnonen R.(PubMed)
(6) Leukoplakia of the vulva locally treated by 13-cis-retinoic acid by Markowska J, Janik P, Wiese E, Ostrowski J.(PubMed)
(7) Dystrophy of the vulva locally treated with 13-cis retinoic acid by Markowska J1, Wiese E.(PubMed)

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