The Effectiveness of Smoothie of formula RRF and Flax Seed for Reduced Symptoms and Treatment of Perimenopause

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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The smoothie for reduced symptoms and treatment of Perimenopause 
Yield: 2 serving (about 8 ounce each)
1 gram of formula RRF(you cam buy them in any Chinese herbal store)
1/2 cup of flax seed
1 cup of grape
1 cup of rice milk

1. Place all ingredients in a blender and puree about 1 minute
2. Blend on high speed about 1 minute or until the mixture is thick and the ice is well crushed. Add more green tea drink if needed
3. Serve immediately

The finding the natural ingredients for reduced symptoms and treatment of Perimenopause  is considered as a dream of many scientist to replace the long usage adverse effect of conventional medicine.
Unfortunately, many compounds found effective in initial studying failed to confirm the potentials in large sample size and multi center.

Recent studies suggested that scientist in some research centers have found the naturally potential ingredients, from Radix Astragali (RA), Radix Angelicae Sinensis (RAS) and Folium Epimedii (FE), three of the extensively applied herbs among traditional Chinese medicines for gynecological disorders(1), including symptoms of Perimenopause.

Long-term treatment of RRF formula exhibited estrogenic properties, inhibited age-associated egeneration may be considered as an alternative/complementary medicine in relieving perimenopausal symptoms(1), according to the joint study lead by the Guangzhou University of Chinese Medicine.

Huang Qi or Bei Qi is also known as Astragalus root. The sweet herb has been used as diuretic agent and to lower blood pressure, increase blood pressure, lessens proteinuria, improve endurance, protect liver function, regulate blood sugar, etc.

In natural aging animal study, Radix Astragali used conjuction with Radix Angelicae Sinensis, and Folium Epimedii in formula RRF, expressed a a positive regulation on the estrogen imbalance and neurotransmitter disorder in restoring reproductive organ degeneration and skeleton deterioration in perimenopausal rats(2).

According to the Guangzhou University Town, RRF also enhanced estradiol (E(2) synthese while diminished the elevated serum FSH and LH levels, attenuated osteoporosis by elevating the BMD levels of total body and bone trabeculae degradation of which induced a capable of acting at multiple targets in the protection and treatment of perimenopausal disorders in midlife women(3).

Furthermore, RRF on study of immunological function, RRF also displayed a relatively wide margin of safety. Dr. Xie JH and colleagues at the joint study lead by the Guangzhou University of Chinese Medicine, Guangzhou said, "Long-term treatment of RRF exhibited estrogenic properties, and retarded certain age-associated degenerations" and "RRF might have the potential for further development as a safe and effective alternative/complementary to conventional medication in relieving perimenopausal symptoms."(4).

On Chinese medicinal plant Radix astragali(RA) alone in the study of 24 ovariectomized female Sprague-Dawley (SD) rats, oral application of RA significantly improved the immune functions of the ovariectomized female rats, but cannot induced the change the sex hormones levels as significantly as estrogen(5).

Dang Qui (Angelica sinensis) is a herb of Genus Angelica from the family Apiaceae, indigenous to China. The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. Use conjunction with Radix Astragali and Folium Epimedii in formula RRF improved the aging degeneration of perimenopausal symptoms in animal study(2).

Folium Epimedii, deciduous or evergreen hardy perennials, native to Asia, and a few in the Mediterranean region has been used in Chinese medicine for induced sexual activity. When used together with Dang qui and Huang qi in formula RRF has shown effectively in enhanced the balancing of diminished hormones due to aging in reduced the expression of perimenopausal symptoms(3).

In take of phytoestrogen with function as weak estrogens, antioxidants, and anti-inflammatory agents(6) plant based lignans, a chemical compoud found in flax seed, may be effective in ameliorated symptoms of peri menopause, according to the joint study lead University of Zurich(7),

The combination of formula RRF and Flax Seed  smoothie may hold a key in further studies in production of an effective natural ingredients for reduced the symptoms displacement and treatment of perimenopause without inducing adverse effects.

Women who are in the perimenopause stage should drink as much as they can, depending to the digestive toleration.

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References

(1) Evaluation of safety of Modified-Danggui Buxue Tang in rodents: Immunological, toxicity and hormonal aspects by Xie JH1, Chen ZW2, Pan YW3, Luo DM3, Su ZR4, Chen HM1, Qin Z5, Huang SQ6, Lei G7.(PubMed)
(2) Perimenopause Amelioration of a TCM Recipe Composed of Radix Astragali, Radix Angelicae Sinensis, and Folium Epimedii: An In Vivo Study on Natural Aging Rat Model by Su JY1, Xie QF2, Liu WJ1, Lai P1, Liu DD1, Tang LH1, Dong TT3, Su ZR4, Tsim KW3, Lai XP4, Li KY5.(PubMed)
(3) Effect of a derived herbal recipe from an ancient Chinese formula, Danggui Buxue Tang, on ovariectomized rats by Xie QF1, Xie JH, Dong TT, Su JY, Cai DK, Chen JP, Liu LF, Li YC, Lai XP, Tsim KW, Su ZR.(PubMed)
(4) Evaluation of safety of Modified-Danggui Buxue Tang in rodents: Immunological, toxicity and hormonal aspects by Xie JH1, Chen ZW2, Pan YW3, Luo DM3, Su ZR4, Chen HM1, Qin Z5, Huang SQ6, Lei G7.(PubMed)
(5) Effects of a Chinese medicinal plant Radix astragali on the ovariectomized female rats by Zheng Y1, Jin Y, Zhu HB, Xu ST, Xia YX, Huang Y.(PubMed)
(6) Urinary phytoestrogen levels and frailty in older American women of the National Health and Nutrition Examination Survey (NHANES) 1999-2002: a cross-sectional study by Eichholzer M1, Richard A, Walser-Domjan E, Linseisen J, Rohrmann S.(PubMed)
(7)  Urinary phytoestrogens and depression in perimenopausal US women: NHANES 2005-2008. by Richard A1, Rohrmann S2, Mohler-Kuo M3, Rodgers S4, Moffat R5, Güth U6, Eichholzer M2.(PubMed)