Posted by Chantel M. research contributed US National Library of Medicine
National Institutes of Health
In
the study to examine the effect of Natto on transplanted human amniotic
fluid mesenchymal stem cells (AFS), Animals were categorized into four
groups: Group I: no treatment; Group
II: fed with Natto (16 mg/day for 7 consecutive days); Group III: AFS
embedded in fibrin glue; Group IV: Combination of group II and III
therapy, posted in PubMed, indicated that the combined therapy caused the most significantly beneficial effects.
Administration of Natto suppressed the inflammatory responses and
correlated with decreased AFS and Schwann cell apoptosis. The decreased
AFS apoptosis was in line with neurological improvement such as
expression of early regeneration marker of neurofilament and late
markers of S-100 and decreased vacuole formation. Administration of
either AFS, or Natto, or combined therapy augmented the nerve
regeneration.
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