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Monday, January 14, 2019

Herbal Aloe Vera, The Potent and Effective Adjunct Therapy for Treatment of Type II Diabetes, Scientist Find

Scientists may have found a natural whole food for treatment of type II diabetes without inducing any side effects, some studies suggested,

Type II diabetes is a chronic acquired medical condition characterized by insufficient insulin entering the bloodstream to regulate the glucose.

The disease is either caused by cells in pancreas dying off or receptor sites clogged up by fat and cholesterol.

In some cases, diabetes is also caused by allergic reactions of cells in the immune system.

The exact cause of type II diabetes is unknown. However, some researchers suggested that the condition is most likely caused by genetic mutation and an unhealthy lifestyle.

Other risk factors associated with the early onset of type II diabetes include overweight or obese, age 45 or older, family history, ethnicity, Alaska Native, high blood pressure and cholesterol and women with polycystic ovary syndrome.

Dr. Waqas Sami, the lead author in the study "Effect of diet on type 2 diabetes mellitus: A review" wrote. "Dietary habits and sedentary lifestyle are the major factors for rapidly rising incidence of DM among developing countries. In type 2 diabetics, recently, the elevated HbA1c level has also been considered as one of the leading risk factors for developing microvascular and macrovascular complications" and "Improvement in the elevated HbA1c level can be achieved through diet management; thus, the patients could be prevented from developing the diabetes complications. Awareness about diabetes complications and consequent improvement in dietary knowledge, attitude, and practices lead to better control of the disease".

These results suggested changes in diet and lifestyle are the most effective method in the management of type II diabetes.

Medication including Alpha-glucosidase inhibitors. Thiazolidinediones (TZDs) Glucagonlike peptide–1 (GLP-1) agonists. Dipeptidyl peptidase IV (DPP-4) inhibitors used for the treatment of type II diabetes may be effective, however, they are to know to induce serious side effects such as low blood sugar, upset stomach, skin rash or itching, weight gain. kidney complications, upset stomach, tiredness or dizziness,... and metal taste.

If you are currently taking one of the above medicine, please make sure that you discuss the side effects with your doctor and know how to deal with them.

Aloe Vera is species of succulent plant in the genus Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan.

The herbal medicine has become very popular for commercial cultivation due to its health benefits. Aloe vera has been used in herbal medicine in treating many kinds of disease, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated of cholesterol, etc..


The Chemical ingredients
The ten main areas of chemical constituents of Aloe vera include amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharide, polysaccharides, salicylic acid, saponins, and sterols.

In the study to examine the clinical effectiveness of aloe vera, a popular herbal remedy in the United Kingdom for the treatment of type II diabetes, researchers at the University of Exeter, launched a review by researching the database of MEDLINE, EMBASE, Biosis, and the Cochrane Library.

Only controlled clinical trials (on any indication) were included in the study.


There were no restrictions on the language of publication. All trials were read and data were extracted in a standardized, pre-defined manner.

After differentiating the 10 selected studies, researchers found that oral administration of aloe vera might be a useful adjunct for lowering blood glucose in diabetic patients as well as for reducing blood lipid levels in patients with hyperlipidemia.

However, the topical application of aloe vera was not an effective preventative for radiation-induced injuries.


Furthermore, Dr. Okyar A and colleagues, in clarifying the controversy over the past 15 years on the hypoglycemic activity of Aloe species, launched an investigation with separate experiments on three main groups of rats, namely, non-diabetic (ND), type I (IDDM) and type II (NIDDM) diabetic rats.

At the end of the experiment, researchers found that

* Application of Aloe vera A. vera leaf pulp and gel extracts were ineffective on lowering the blood sugar level of ND rats.

* A. vera leaf pulp extract showed hypoglycemic activity on IDDM and NIDDM rats, the effect being enhanced for type II diabetes in comparison with glibenclamide.

* On the contrary, A. vera leaf gel extract showed hyperglycaemic activity on NIDDM rats.

These results suggested, pulps of Aloe vera leaves devoid of the gel could be useful in the treatment of non-insulin dependent diabetes mellitus.

Taken all together Aloe Vera may be considered an adjunct therapy for treatment in patients non-insulin-dependent type 2 diabetes.

However, due to the limitation of the above studies, additional data collection large example size and multi-centers studies performed with human consumption of the whole food Aloe vera during the course of the disease will be necessary to complete the picture of Aloe vera anti-diabetes possibilities.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Aloe vera: a systematic review of its clinical effectiveness. by Vogler BK, Ernst E.(PubMed)
(2) Hypoglycemic and hypolipidemic effects of processed Aloe vera gel in a mouse model of non-insulin-dependent diabetes mellitus. by Kim K, Kim H, Kwon J, Lee S, Kong H, Im SA, Lee YH, Lee YR, Oh ST, Jo TH, Park YI, Lee CK, Kim K.(PubMed)
(3) Effect of Aloe vera leaves on blood glucose level in type I and type II diabetic rat models.
Okyar A, Can A, Akev N, Baktir G, Sütlüpinar N.(PubMed)
(4) Effect of diet on type 2 diabetes mellitus: A review by Waqas Sami,1,2 Tahir Ansari,3 Nadeem Shafique Butt,4 and Mohd Rashid Ab Hamid. (PubMed)

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