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Wednesday, September 26, 2012

Phytoestrogen consumption and ovarian cancer

 Posted by Chantel M. research contributed  US National Library of Medicine National Institutes of Health

In  a population-based case-control study to evaluate phytoestrogen intake from foods and supplements and epithelial ovarian cancer risk of a total of 205 cases and 390 controls were included in analyses., posted in PubMed, there was a suggestion of an inverse association with total phytoestrogen consumption (from foods and supplements), with an odds ratio (OR) of 0.62 (95% CI: 0.38-1.00; p for trend: 0.04) for the highest vs. lowest tertile of consumption, after adjusting for reproductive covariates, age, race, education, BMI, and total energy. Further adjustment for smoking and physical activity attenuated risk estimates (OR: 0.66; 95% CI: 0.41-1.08). There was little evidence of an inverse association for isoflavones, lignans, or coumestrol.

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