Alcohol toxicity is a result of excessive consumption of alcohol that leads to alcohol poisoning.
People with a high level of blood alcohol may experience symptoms of confusion, unresponsiveness, and disorientation.
If severe cases, patients may lose conscientiousness or go into a coma.
Long- term excessive alcohol consumption may cause liver damage, leading to the symptoms of jaundice, cirrhosis, liver failure, and liver cancer.
Some people may experience symptoms of alcohol withdrawal symptoms after a day of heavy drinking day. Depending on the body response, some people may experience alcohol withdrawal symptoms as early as two hours after the last drink.
However, most people may experience the symptoms as soon as they wake up after a night of sleep. The symptoms will peak within the first 24 to 48 hours.
The most common alcohol withdrawal symptoms are a rapid heartbeat, changes in blood pressure, sweating, tremors, and fever.
The cucumber plant is a species of Cucumis Sativus, belongings to the family Cucurbitaceae and native to Western Asia. It is a creeping vine with roots in the ground and grows up with the support of frames.
With an aim to find a natural compound which processes anti-alcoholic toxicity, researchers investigated the heat-treated cucumber juice protective effect on blood alcohol levels and hepatic alcohol metabolic enzyme system in experimental rats.
The study included alcoholic toxicity rats orally dosed to 22% alcohol (6ml/kg body weight) along with different concentrations of heat-treated cucumber juice (10, 100 and 500mg/kg) and commercial goods for hangover-removal on sale (2ml/kg).
According to the tested results, after 7h, all concentrations of heat-treated cucumber remarkable reduced the blood alcohol levels.
Furthermore, levels of dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) enzymatic activities associated with a detoxicity in rat liver at 9h after alcohol administration were also increased in the treated rats.
The effect of heat-treated cucumber juice on alcohol detoxification was observed only in the rats treated before 30min from alcohol administration may be involved in stimulated blood alcohol metabolism.
Based on the finding, researchers said, "These findings indicate that heat-treated cucumber juice has a significant protective effect on alcohol detoxification in experimental rats, suggesting its usefulness in the treatment of the liver injury caused by alcohol consumption".
Taken altogether, heat-treated cucumber may be used for the prevention and treatment of alcoholic toxicity, pending to the confirmation of the larger sample size and multicenter human study.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Protective effect of heat-treated cucumber (Cucumis sativus L.) juice on alcoholdetoxification in experimental rats by Bajpai VK1, Kim NH2, Kim JE3, Kim K4, Kang SC. (PubMed)
(2) NADPH-dependent reductases involved in the detoxification of reactive carbonyls in plants by Yamauchi Y1, Hasegawa A, Taninaka A, Mizutani M, Sugimoto Y. (PubMed)
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