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Wednesday, February 5, 2020

Organic Cabbage Inhibits the Risk of Gastric Cancer in Vitro

The stomach located between the esophagus and the small intestine is a muscular, hollow and important organ of the digestive tract.

Gastric or stomach cancer is a chronic condition characterized by irregular cell growth in the tissues of the stomach.

Most cases of gastric cancer start in the cells on the surface of the inner lining of stomach tissue.
Due to the small size at the early stage, gastric cancer is asymptomatic.

However, at the later stage, after penetrating into the deeper layers of the stomach, the cancer cell may travel a distance away to infect other healthy tissues and organs, leading to secondary metastasis.

According to the statistics provided by the American Cancer Society, in 2019, approximately, 27,510 cases of stomach cancer will be diagnosed (17,230 in men and 10,280 in women) and 11,140 people will die from gastric cancer (6,800 men and 4,340 women).

Overall, the 5-year survival rate for people with gastric cancer is 31%. Cancer diagnosed at the localized stage have a 5 years survival rate of 67%.

Gastric adenocarcinoma is a type of cancer that arises from the glands in the mucosa, including
* Superficial spreading
It is an early stage of cancer and tends to be less aggressive or ulcer.

* Polyploid
Cancer grows in a pattern like a polyp and is less aggressive.

* Infiltrating
If cancer grows in infiltrating pattern into the stomach wall and more aggressive.

* Linitis plastica
Cancer grows diffusivity throughout the whole wall of the stomach.

Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem of which is crowded a mass of leaves, usually green but in some varieties, it may be red or purplish.

With an aim to find a natural food for the prevention of cancers, researchers examined the effect of cabbage extract on gastric cancer cells.

According to the tested differentiation, organic fresh cabbage contained significantly less total flavonoids in both years of experiments compared to the conventional one, including several flavonoid compounds, total chlorophylls, carotenoids, nitrites, and nitrates.

Furthermore, the organic sauerkraut juice contained significantly more total polyphenols (5.39 ± 0.22 mg/100 g FW and 9.05 ± 1.10 mg/100 g FW) and several flavonoids compared to the conventional one.

Compared to only CONV sauerkraut juice produced with the highest N level of fertilization induced a statistically significant increase in the level of necrosis of human stomach gastric adenocarcinoma cell line AGS, all sauerkraut juice exerted anti-apoptotic activity in gastric adenocarcinoma cells.

Taken altogether, cabbage processed abundantly bioactive compounds including nitrites, and nitrates may be considered a remedy for the prevention and treatment of gastric cancer, pending to the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The Nutritive Value of Organic and Conventional White Cabbage (BrassicaOleracea L. Var. Capitata) and Anti-Apoptotic Activity in Gastric AdenocarcinomaCells of Sauerkraut Juice Produced Therof by Hallmann E1, Kazimierczak R1, Marszałek K2, Drela N3, Kiernozek E3, Toomik P4, Matt D5, Luik A5, Rembiałkowska E. (PubMed)

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