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Tuesday, April 23, 2013

Gestational diabetes mellitus (GDM) and Obesity

Posted by Chantel M. Research contributed by the US National Library of Medicine National Institutes of Health
The prevalence of childbearing age obesity is wide spreading in US, approximately, 50% of them are either overweight [body mass index (BMI) 25-29.9 kg/m(2)] or obese (BMI ≥ 30 kg/m(2)).
Obese pregnant women are at higher risk to develop Gestational diabetes mellitus (GDM). According to the study by the Case Western Reserve University at MetroHealth Medical Center, in the study of Participants underwent a 75-g oral glucose tolerance test (OGTT) between 24 and 32 weeks pregnancy to determine associations of gestational diabetes mellitus (GDM) and obesity with adverse pregnancy outcomes in the Hyperglycemia and Adverse Pregnancy Outcome (HAPO), posted in PubMed, showed that mean maternal BMI was 27.7, 13.7% were obese (BMI ≥33.0 kg/m(2)), and GDM was diagnosed in 16.1%. Relative to non-GDM and nonobese women, odds ratio for birth weight >90th percentile for GDM alone was 2.19 (1.93-2.47), for obesity alone 1.73 (1.50-2.00), and for both GDM and obesity 3.62 (3.04-4.32).

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