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Tuesday, April 30, 2013

Obesity and infertility management in women with polycystic ovary syndrome

Posted by Chantel M. Research contributed by the US National Library of Medicine National Institutes of Health
The prevalence of childbearing age obesity is wide spreading in US, approximately, 50% of them are either overweight [body mass index (BMI) 25-29.9 kg/m(2)] or obese (BMI ≥ 30 kg/m(2)).
Obesity and infertility management in women with polycystic ovary syndrome
Obesity has become a worldwide epidemic with ever increasing incidence and public health problems in both developing and developed countries. According to the Kuwait University, in the study of 270 of women with polycystic ovarian syndrome attending the infertility clinic were evaluated clinically, biochemically, and laparoscopically, posted in PubMed, indicated that significantly more obese women had oligomenorrhoea (p<0.01) and anovulation (p<0.01) than women with normal weight. Obesity adversely affected the outcome of ovulation induction with clomiphene citrate and gonadotrophins; 79% of women with BMI 18-24 ovulated at 6 months compared to 15.3% in those with BMI 30-34 (p<0.001) and 11.8% in women with BMI > or = 35 (p<0.001). The pregnancy rate and outcome were also adversely affected by obesity.

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