According to the study of " Neuromodulation by soy diets or equol: anti-depressive & anti-obesity-like influences, age- & hormone-dependent effects." by Blake C, Fabick KM, Setchell KD, Lund TD, Lephart ED. (Source from Department of Physiology and Developmental Biology and The Neuroscience Center, Brigham Young University, Provo, Utah 84602, USA.), posted in
US National Library of Medicine National Institutes of Health, researchers found that Consumption of dietary isoflavones or equol exposure in rats has body weight controlling effects and equol specifically may have antidepressant potential dependent upon diet initiation and/or dosage of treatments. The current study demonstrates that equol is able to decrease body weight, abdominal WAT, and depressive-related behavior. While other factors and mechanisms may play a role, in part, the present results provide a greater understanding of how isoflavonoid molecules modulate the brain's influence on behavior.