Posted by Chantel M. Contributed by American Journal of Clinical Nutrition, Vol. 83, No. 5, 1118-1125, May 2006 © 2006 American Society for Nutrition
In a study of "Soy isoflavones modulate immune function in healthy postmenopausal women" by Tracy A Ryan-Borchers, Jean Soon Park, Boon P Chew, Michelle K McGuire, Lisa R Fournier and Kathy A Beerma, researcher found that Isoflavone intervention in postmenopausal women resulted in higher (P < 0.05) B cell populations and lower (P < 0.05) plasma concentrations of 8-hydroxy-2-deoxy-guanosine, an oxidative marker of DNA damage. Isoflavone treatment did not significantly influence concentrations of interferon γ, interleukin 2, tumor necrosis factor α, or C-reactive protein in plasma or of 8-isoprostane in urine and concluded that soymilk and supplemental isoflavones modulate B cell populations and appear to be protective against DNA damage in postmenopausal women.