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Friday, September 19, 2014

Herbal Crinum asiaticum and Hair Loss

Posted by Chantel Martiromo

Decreased hormonal secretions due to aging stimulates the production of the enzyme 5-alpha reductase to converse testosterone to gihydro-testosterones DHT, affecting hair to grow back thinner or not grown back at all.  DHT shrinks the follicles, causing hair thins and hair receded at the forehead, crown and temple for men and thins over the entire scalp for women. Herbal treatment for hair loss has existed throughout human history, but epidemiological studies, linking herbs effectiveness in treating hair loss have produced inconsistent results.

Androgenetic alopecia is a common hair loss in men and women. In men, it causes baldness patterns, receding at the forehead. In women, the hair becomes thinner all over the head, and the hairline does not recede.
Crinum asiaticum is a genus of Crimum, belonging to the family Amaryllidaceae, native to Jeju Island, Korea. The herb has been used in habal medicne for treatments of injury and inflamed joints, swellings, swollen joints, lumbago, pains and in cases of headache, fever, etc. Topical application of the EtOH extract of C. asiaticum onto the back of C57BL/6, increased the proliferation of immortalized vibrissa dermal papilla cells, cell nuclear antigen (PCNA) in the bulb region and the hair-fiber lengths of vibrissa(12). Norgalanthamine, a chemical constituent of Crinum asiaticum, also induced anagen progression of the hair shaft, increased the proliferation of immortalized vibrissa dermal papilla cells(13).
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References

(12) Promotion effect of norgalanthamine, a component of Crinum asiaticum, on hair growth by Kim SC, Kang JI, Kim MK, Hyun JH, Boo HJ, Park DB, Lee YJ, Yoo ES, Kim YH, Kim YH, Kang HK.(PubMed).
(13) Promotion effect of norgalanthamine, a component of Crinum asiaticum, on hair growth by Kim SC, Kang JI, Kim MK, Hyun JH, Boo HJ, Park DB, Lee YJ, Yoo ES, Kim YH, Kim YH, Kang HK.(PubMed)

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