Herbal Ishige sinicola and Hair Loss

Posted by Chantel Martiromo

Decreased hormonal secretions due to aging stimulates the production of the enzyme 5-alpha reductase to converse testosterone to gihydro-testosterones DHT, affecting hair to grow back thinner or not grown back at all.  DHT shrinks the follicles, causing hair thins and hair receded at the forehead, crown and temple for men and thins over the entire scalp for women. Herbal treatment for hair loss has existed throughout human history, but epidemiological studies, linking herbs effectiveness in treating hair loss have produced inconsistent results.

Androgenetic alopecia is a common hair loss in men and women. In men, it causes baldness patterns, receding at the forehead. In women, the hair becomes thinner all over the head, and the hairline does not recede.
Ishige sinicola is a genus of brown algae (class Phaeophyceae), belonging to the family Ishigeaceae native to native to Jeju Island, Korea. Topical application of I. sinicola extract onto the back of C57BL/6 mice inhibit anagen progression of the hair shaft and activity of the activity of 5α-reductase, increased cell proliferation vibrissa dermal papilla cells (DPCs), downregulated p27kip1 in stopping or slowing down the cell division cycle(13).
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References 
(13) The promoting effect of Ishige sinicola on hair growth by Kang JI, Kim EJ, Kim MK, Jeon YJ, Kang SM, Koh YS, Yoo ES, Kang HK.(PubMed)