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Wednesday, January 15, 2020

Asparagus, the Antioxidant Natural Whole Food

Asparagus, one the miracle food is found to process significant antioxidant effects in enhancing the immune system fighting against the forming of free radicals and foreign invasion.

An antioxidant is a molecule inhibited oxidative free radicals before they can cause any damage to the host, through domino's activities.

According to the joint study lead by the National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, extracts of Asparagus cochinchinensis (AC) exhibited anti-inflammatory effects by inhibited H2O2-induced cell death in cultured cortical neurons in protection against the free radical causes of depressant and neuro cells apoptosis.


Asparagus is a flowering plant belongs to species the genus Asparagus, native to the western coasts of northern Spain, north to Ireland, Great Britain, and northwest Germany, northern Africa, and western Asia, used from early times as a vegetable and medicine, because of its delicate flavor and diuretic properties.

Dr. Lee JW1, the lead researcher suggested, these effects appear to be associated with activation of the Shp-2, antibody, and ErK1/2 Akt and Akt pathways involved the cell apoptosis, cell proliferation.

The study of four fractions viz. methanol (MF), ethyl acetate (EF), n-Butanol (BF), and precipitated aqueous (PAF) of A.racemosus root also found that the constituents exerted significantly antioxidant properties in inhibition of free radicals by raising serum antioxidant enzymes such as. superoxide dismutase and reduced glutathione and catalase.

The 4 factions also induced hepaprotective activity through inhibition of the formation of lipid peroxides in the liver of rats pretreated with the extracts.

Furthermore, in a total of 80 Kun Ming mice randomly divided into four groups (20/group), the mice in the control group received a daily subcutaneous injection of saline; A daily injection of D-galactose administered to the aging model group, the vitamin C (Vc) group (positive control group), and the extract treatment group, group with extract treatment, the aqueous extract of A. cochinchinensis (Lour.) Merr. increased antioxidant effects of nitric oxide synthase (NOS), catalase (CAT), superoxide dismutase (SOD) activities, and reduced the MDA content, a marker for oxidative stress (p < 0.05), in compared with other groups.

In vivo and in vitro, Dr, Lei L the lead author of the study said, " The aqueous extract of A. cochinchinensis (Lour.) Merr. shoot had a strong radical scavenging capability in vivo and in vitro, and might be used to diminish radicals in the body and consequently prevent aging".




In fact, the efficacy of asparagus probably is due to the presence of abundant phytochemicals flavonoids, phenolics, and best antioxidant potential among different fractions of crude methanol extract such as catechin, caffeic acid, rutin, myricetin, and quercetin, according to the Quaid-i-Azam University.

There is no doubt that asparagus may be the best antioxidant whole food used to improve the immune system against the free radical cause of diseases. People with weakened immunity due to aging should add a portion of asparagus into their diet.


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Sources
(1) Bioactive compounds, antioxidant and binding activities and spear yield of Asparagus officinalis L. by Lee JW1, Lee JH, Yu IH, Gorinstein S, Bae JH, Ku YG.(PubMed)
(2) Antioxidant and hepatoprotective action of Asparagus racemosus Willd. root extracts by Acharya SR1, Acharya NS, Bhangale JO, Shah SK, Pandya SS.(PubMed)
(3) The antioxidant effect of Asparagus cochinchinensis (Lour.) Merr. shoot in D-galactose induced mice aging model and in vitro by Lei L1, Ou L2, Yu X3.(PubMed)
(4) HPLC-DAD analysis, antioxidant potential and anti-urease activity of Asparagusgracilis collected from District Islamabad by Shah NA, Khan MR1, Sattar S, Ahmad B, Mirza B.(PubMed)

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