Ginger, the Pungent Spice Which inhibits the Onset and Progression of Arthritis

Scientists may have found a whole food which processes a significant effect in reducing and treatment of arthritis with no side effects, some studies found.

Arthritis is a class of inflammatory diseases that affect the joints.

The most common symptoms of arthritis are joint pain and stiffness.


However, some patients with arthritis may also experience symptoms of redness, warmth, swelling, and decreased range of motion of the affected joints.

The most common causes of arthritis are the improper health of the joint injury in the younger age and infections that affect the integrity of the cartilage.

RA, an autoimmune disorder is a type of arthritis caused by the immune system mistakenly attacks the joints tissues of the body.

The prevalent risk factors associated with the onset of the disease include the increase in age, family history, gender, ethnicity, and obesity.

Some researchers suggested that people who follow the Western diet with high saturated and trans fat, red meat and processed foods and fewer fruits and vegetables and whole grains are also at the increased risk of arthritis.

According to the study published in the journal JCI Insight on April 19, by the University of Rochester Medical Center in New York, after 3 months of feeding mice a high-fat diet similar to that of a western “cheeseburger and milkshake” regimen, the mice became obese and diabetic and fat percentage was double compared to mice fed with a healthy, low-fat diet.

The contribution of overweight obesity caused by long-term intake of the Western diet may contribute to the link of obesity in the risk of arthritis.

Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.

The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.

With an aim to reconfirm the traditional medicine use of ginger for the treatment of chronic inflammatory diseases, the research team at the examine the turmeric (rich in curcuminoids) and ginger (rich in gingerols and shogaols) rhizomes effect in patients with arthritis rat adjuvant-induced arthritis (AIA) both plants at the dose 200 mg/kg body weight were orally administrated.

Turmeric and ginger exerted a significantly suppressed (but with different degrees) the incidence and severity of arthritis by increasing the production of anti-inflammatory and decreasing pro-inflammatory cytokines.

Both turmeric and ginger also restored the antioxidant enzymes in the rats.


In the anti-arthritic activity, turmeric was more effective compared to those of ginger and indomethacin (a non-steroidal anti-inflammatory drug), especially when the treatment started from the day of arthritis induction.


Interestingly, the percentage of disease recovery was 4.6-8.3% and 10.2% more in turmeric compared with ginger and indomethacin, respectively.

Dr. the lead author said, after taking into account of co and confounders, "the anti-inflammatory/anti-oxidant activity of turmeric over ginger and indomethacin, which may have beneficial effects against rheumatoid arthritis onset/progression as shown in AIA rat model".

The findings indicated a potential effect of ginger against arthritis although to a lesser extent than those of turmeric.

Furthermore, the investigation of the potential of hydroalcoholic extract of Zingiber officinale rhizomes (Z. officinale extract) in ameliorating inflammatory process in rat collagen-induced arthritis, also found that* Z. officinale extract in doses higher than 50 mg/kg/day intraperitoneally significantly enhanced the immune function against the progression of arthritis.

* Continued administration of the said volume for 26 days can ameliorate the clinical scores, disease incidence, joint temperature and swelling, and cartilage destruction.

* The anti-arthritis effects were associated with reduced production of proinflammatory cytokines and antibody.

Most importantly, Z. officinale extract at the dose of 200 mg/kg/day was more superior to those of 2 mg/kg/day of indomethacin compared by most of the measured parameters.

Taken altogether, ginger may be used as a functional food for the prevention and combined with primary medicine for the treatment of arthritis


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.



Sources
(1) Anti-inflammatory and anti-oxidant properties of Curcuma longa (turmeric) versus Zingiber officinale (ginger) rhizomes in rat adjuvant-induced arthritis by Ramadan G1, Al-Kahtani MA, El-Sayed WM. (PubMed)
(2) Evaluation of the effect of hydroalcoholic extract of Zingiber officinale rhizomes in rat collagen-induced arthritis by Fouda AM1, Berika MY. (PubMed)
(3) Western Diet, With Its High-Fat Content, Linked To ArthritisApr 19, 2018 09:00 AM By Sadhana Bharanidharan, (Medical Daily)