Beet, The Best in Prevention and Treatment of Bladder Cancer

Intake of function food beet root regularly not only lowers the early occurrence but also provides a natural treatment of bladder cancer without inducing adverse effects.

Bladder cancer is a medical condition characterized by irregular cell growth and multiplied disorderly and uncontrollably in bladder tissues.

Beet, best known as the beetroot or garden beet and belonging to the amaranth family, is a perennial plant with leafy stems growing to 1–2 m tall.

According to the University of Urbino 'Carlo Bo', betaxanthins and betacyanins, isolated from beetroot exerted a significant anti-cancer effect in testing bladder cancer cell lines, through the expression of antioxidant and pro-apoptotic activities.

The anti-cancer property of beetroot also displayed a strong anti-angiogenesis by blocking the cancer cell in established new blood vessel signalling.


When used combination with Vitexin-2-O-xyloside, an apigenin flavone glucoside, betaxanthins and betacyanins also exerted a strong antiproliferative activity in bladder cancer cell lines, intrinsically and extrinsically in the expression of apoptosis.

The study also indicated that this combination when used conjunction in conventional chemotherapy not only enhanced the effectiveness of treatment in bladder cancer but also overcome the adverse effect of toxicity and multidrug resistance of cancer cells.


Furthermore, in other study conducted by the same university, Betacyanins (BC) purified from beetroot (Beta vulgaris var. rubra L.) tested, alone or in combination with vitexin-2-O-xyloside (XVX) also isolated from the same vegetable enhanced the ability to reduce the proliferation rate in T24 bladder cancer cells, synergistically by inhibition of protein of gene in promoted cell survival and enhanced cancer apoptosis.

Taking together, a diet enriched with these bioactive molecules of beetroot could be used as a functional food in the prevention and treatment of human bladder cancer.


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Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) C-Glycosyl Flavonoids from Beta vulgaris Cicla and Betalains from Beta vulgaris rubra: Antioxidant, Anticancer and Antiinflammatory Activities-A Review by Ninfali P1, Antonini E1, Frati A1, Scarpa ES1.(PubMed)
(2) Betacyanins enhance vitexin-2-O-xyloside mediated inhibition of proliferation of T24 bladder cancer cells by Scarpa ES1, Emanuelli M2, Frati A1, Pozzi V2, Antonini E1, Diamantini G1, Di Ruscio G3, Sartini D3, Armeni T3, Palma F1, Ninfali P1.(PubMed)
(3) C-Glycosyl Flavonoids from Beta vulgaris Cicla and Betalains from Beta vulgaris rubra: Antioxidant, Anticancer and Antiinflammatory Activities-A Review by Ninfali P1, Antonini E1, Frati A1, Scarpa ES1.(PubMed)