Ginger, Relieves Pain and Reduced Disability of Patients with Osteoarthritis

Ginger may have a potential and positive effect in ameliorating the symptoms of pain and complication of reduced quality of life in patients with osteoarthritis, some scientists suggested.

Osteoarthritis (OA) is a chronic condition of a type of joint disease characterized by the breaking down of joint cartilage and underlying bone due to “wear and tear” of joints over time.

Some researchers suggested that OA is a degenerative disease characterized by “low-grade inflammation” in cartilage and synovium, affecting the joint structure and progressive deterioration of cartilage.

According to the statistic from the NIH, osteoarthritis (OA) is the most common joint disorder in the US. Among adults, 60 years of age or older the prevalence of symptomatic knee and sadly OA affects approximately 10% in men and 13% in women.

Epidemiological strongly suggested that obese and overweight which have a strong impact on the weight-bearing joints, genetic preposition of a patient can make such patient more susceptible to the disease compared to others do not, people with a joint injury that did heal properly in the younger age and people with occupations that require standing for long periods of time, repetitive bending, heavy lifting or other movements and the increase in age are associated to the increased risk of the onset of the disease.

The most common symptoms of osteoarthritis are joint pain and stiffness.

Dr. Giuseppe Musumeci, the lead author in the study "Osteoarthritis in the XXIst Century: Risk Factors and Behaviours that Influence Disease Onset and Progression" suggested that besides the risk factors mentioned above, dietary factors also play an important role for the onset of the disease.

In the dietary aspect in the induction of OA, the research team wrote, "This diet (The Western diet) is mainly constituted by preservative and harmful substances, such as animal fat and glucose excessive concentration and lack of nutritional factors, such as vitamins and nutrient minerals essential for our body. Moreover, the bad dietary habits may predispose people to obesity, which is responsible for both metabolic destroying processes affecting the cartilage and overload of the joints, especially hips and knees".

And, " quantity and quality of nutrient intake. Low intake of vitamin D and vitamin C is a possible risk factor for knee OA, while certain food groups, such as milk and dairy products, meat and poultry are beneficial for knee OA. Thus we could affirm that nutritional imbalance, combined with endocrine abnormalities, may be involved in the pathogenesis of OA".

Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.

The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.

With an aim to reaffirm the traditional use of ginger for the treatment of osteoarthritis, a joint review led by the Copenhagen University Hospital, Bispebjerg and Frederiksberg were conducted to assess the clinical efficacy and safety of oral ginger for the symptomatic treatment of osteoarthritis (OA).

The study was carried out by searching the randomized controlled trials (RCTs) comparing oral ginger treatment with placebo in OA patients aged >18 years satisfied the predetermined guidelines and criteria, including the outcomes of the reduction in pain and disability.

Out of 122 retrieved references, 117 were discarded, only 5 five trials (593 patients) were selected for meta-analyses.

All 5 remained studies suggested that ginger intake scored a statistically significant pain reduction.


Furthermore, the application of ginger in subjects with osteoarthritis demonstrates a statistically significant reduction in disability compared to control.


However, according to the returned questionnaires from the participants, researchers surprisingly found that patients given ginger are more than twice as likely to discontinue treatment compared to placebo.


Dr. Mozaffari-Khosravi H, the lead author, launched a joint study to determine the ginger powder effects in relieving pain and inflammation in patients with osteoarthritis.

120 participants selected for the randomized double-blind placebo-controlled 3-month clinical trial for knee osteoarthritis were randomly assigned to one of two groups: the ginger group (GG) or the placebo group (PG).

Ginger selected group was given capsules containing 500 mg of ginger powder, while the PG group was given capsules filled with 500 mg starch.

At the baseline, proinflammatory cytokine concentrations did not differ by group, observed by the participant's blood sample.

After 3 months, GG showed a significant reduction of cytokines compared to the PG.

In the final report, the research team wrote, "ginger supplementation may have promising benefits for knee osteoarthritis".

These results reconfirming the use of ginger for the treatment of osteoarthritis in traditional medicine with no side effects

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.




Sources
(1) Efficacy and safety of ginger in osteoarthritis patients: a meta-analysis of randomized placebo-controlled trials by Bartels EM1, Folmer VN2, Bliddal H2, Altman RD3, Juhl C4, Tarp S2, Zhang W5, Christensen R. (PubMed)
(2) Effect of Ginger Supplementation on Proinflammatory Cytokines in Older Patients with Osteoarthritis: Outcomes of a Randomized Controlled Clinical Trial by Mozaffari-Khosravi H1,2, Naderi Z1, Dehghan A3, Nadjarzadeh A1, Fallah Huseini H. (PubMed)
(3) Osteoarthritis in the XXIst Century: Risk Factors and Behaviours that Influence Disease Onset and Progression by Giuseppe Musumeci,1,* Flavia Concetta Aiello,1 Marta Anna Szychlinska,1Michelino Di Rosa,2 Paola Castrogiovanni,1 and Ali Mobasheri. (PubMed)