White Button Mushroom Protects the Heart and Blood Vessels Against Cardiovascular Disease (CVD)

Scientists may have found one of the natural food used in many different cultures with potential in reduced risk and protected against CVD.

Cardiovascular disease (CVD) is a group of conditions associated with the abnormal functioning of the heart and blood vessels.

The causes of cardiovascular diseases are associated with certain prevalent risk factors, including metabolic syndrome, diabetes, and prediabetes, smoking, family history, an increase in age and being overweight or obese.

Some researchers suggested that the coincidence of overweight and obesity and cardiovascular diseases has increased proportionally over a few decades probably correlated to the promotion of the Western diet with high fat, salts, and sugar.

Dr. Luma Akil, the lead author in the concerns of the obesity causes of elevated cardiovascular disease (CVD) mortality and morbidity among the American adults conducted an.examination of the associations between the increase in body mass index (BMI) and the increased rates of CVD and high blood pressure (HBP) in the states of Mississippi, Alabama, Louisiana, Tennessee, and Colorado

The study included the data from the Behavioral Risk Factor Surveillance System were obtained and analyzed for obesity rates, percent of myocardial infarction, stroke, and HBP from 2005–2009.

Using regression analysis, researchers found that the highest rates of obesity, CVD, and HBP were found in Mississippi, while Colorado had the lowest rates.

The result suggested that maintaining a healthy weight helps reduce the risks of developing CVD and obesity is among the leading causes of elevated cardiovascular disease (CVD) mortality and morbidity.

In other words, regular consumption of fruits and vegetables is strongly associated with a reduced risk of cardiovascular disease (CVD). Dietary fungi, such as, mushrooms, can protect against chronic disease by altering inflammatory environments through inhibition of cellular processes under pro-inflammatory conditions which are associated with CVD,

Mushroom, a standard name of white button mushroom, the fleshy, spore-bearing fruiting body of a fungus produced above ground on soil or on its food source, contains several important nutrients including Thiamine (Vitamin B1), Riboflavin (Vitamin B2), Niacin (Vitamin B3), Pantothenic acid (Vitamin B5), Calcium, Phosphorus, Potassium, Sodium, Selenium, Iron, Copper and Zinc which are necessary to maintain the growth, body functions as well as protected against chronic diseases.

According to Dr. Martin KR., ergothioneine (ERT), a novel antioxidant, presented in edible mushrooms, accumulated through diet was found effective in interrupting pro-inflammatory induction of adhesion molecule expression associated with atherogenesis(1).

Its antioxidants such as Astraodorol, Psilocybin, Lectin, adustin, ribonuclease, nicotine, etc. may also consist the magic power in reduced risk and treatment of vary types of cancer, including colon(4), breast and gastric cancers(5) through inhibition of cell cycle arrest, significant suppression of cellular proliferation, in tested cancer cell lines.

These findings showed to support the notion of dietary mushrooms in the protection of CVD, but multi canters and large sample size studies to identify the main ingredients comparable to the current medicine used are necessary to improve its validation.

But, the study of the University of Gdańsk, in the reviews and updates data on macro and trace elements and radionuclides in edible wild-grown and cultivated mushrooms suggested that the coexistence of minerals of nutritional value collected from natural habitats, and co-occurrence with some hazardous elements including Cd, Pb, Hg, Ag, As, and radionuclides should be taken certain precautions(6).

Taken altogether, white button mushroom may be considered a functional food for the prevention and treatment of cardiovascular diseases, depending on the confirmation of the larger sample size and multi-center human study.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) The bioactive agent ergothioneine, a key component of dietary mushrooms, inhibits monocyte binding to endothelial cells characteristic of early cardiovascular disease by Martin KR.(PubMed)
(2) Both common and specialty mushrooms inhibit adhesion molecule expression and in vitro binding of monocytes to human aortic endothelial cells in a pro-inflammatory environment by Martin KR.(PubMed)
(3) Macro and trace mineral constituents and radionuclides in mushrooms: health benefits and risks. by Falandysz J1, Borovička J.(PubMed)
(4) Intracellular trafficking and release of intact edible mushroom lectin from HT29 human colon cancer cells Lu-Gang Yu1, David G. Fernig2 an Jonathan M. Rhodes (The Febs Journal)
(5) Commonly consumed and specialty dietary mushrooms reduce cellular proliferation in MCF-7 human breast cancer cells by Martin KR1, Brophy SK.(PubMed)
(6) Macro and trace mineral constituents and radionuclides in mushrooms: health benefits and risks. by Falandysz J1, Borovička J.(PubMed)
(7) Fruit and vegetable consumption and all-cause, cancer and CVDmortality: analysis of Health Survey for England data by Oyebode O1, Gordon-Dseagu V, Walker A, Mindell JS.(PubMed)
(8) Seasonal consumption of salad vegetables and fresh fruit in relation to the development of cardiovascular disease and cancer by Cox BD1, Whichelow MJ, Prevost AT.(PubMed)
(9) Intakes of fruits, vegetables and carbohydrate and the risk of CVD by Joshipura KJ1, Hung HC, Li TY, Hu FB, Rimm EB, Stampfer MJ, Colditz G, Willett WC.(PubMed)
(10) Relationships between Obesity and Cardiovascular Diseases in Four Southern States and Colorad by Luma Akil, PhD-C, Candidate and H. Anwar Ahmad, PhD, MBA, MCIS, Faculty. (PMC)