Navy Beans Normalize the Levels of Blood Cholesterol

Hyperlipidemia is a condition associated with abnormally high levels of fat including cholesterol in the blood.

Hypercholesterolemia is a condition characterized by abnormally high levels of cholesterol in the bloodstream.

Most cases of hypercholesterolemia is a result caused by either overexpression of low-density lipoprotein (LDL) or low levels of high-density lipoprotein (HDL).

Cholesterol converted to bile acids is a waxy substance produced by the liver or the dietary sources in moderate amount plays a critical to aid digestive function, build strong cell membranes, produce steroid hormones and vitamin D.


However, excessive amounts of low-density cholesterol in the blood have been found to induce plaque built-up on the arterial wall, leading to heart disease and stroke.

Similar to high blood pressure, people with hypercholesterolemia are asymptomatic. However, patients with familial hyper cholesterol may experience symptoms of chest pain with activity. xanthomas, and cholesterol deposits around the eyelids.

Hypercholesterolemia associated with forming plaques on the arterial wall that induces coronary artery disease (CAD), the leading cause of death in the US.


In the US, approximately, 71 million American adults (33.5%) have high low-density lipoprotein (LDL), or “bad,” cholesterol, and only 1 out of every 3 adults with high LDL cholesterol has the condition under control.

Sadly, 50% of people with hypercholesterolemia are not getting treatment.

Out of many risk factors associated with the risk of hypercholesterolemia, some researchers suggested that aging may have a strong impact on the increased incidence in the US.


Dr. Laura Trapani, the lead scientist wrote, "description of age-related disruption of lipid homeostasis, which particularly affects 3-hydroxy 3-methylglutaryl Coenzyme A reductase, the key rate-limiting enzyme".

And, "gender-related dysregulation of this enzyme, providing new evidence for the different mechanisms driving dyslipidemia in elderly men and women. In addition, we introduce pharmacological methods of regulating HMGR and maintaining cholesterol homeostasis".

In other words, aged related dysregulation of 3-hydroxy 3-methylglutaryl Coenzyme A reductase enzyme may be the culprit associated with the onset of cholesterolemia in the older population.


The small, white navy bean, also called pea bean or haricot, popular in both dry and green forms, is very popular in Britain and the US, native to Peru. It is now grown and consumed across the world, due to its numerous health benefits.

With an aim to find a potential ingredient for the prevention and treatment of high blood cholesterol, researchers investigated the navy beans and rice bran efficacy in the regulation of serum cholesterol in hypercholesterolemic adults.

The study included children aged 8 to 13 years who are at risk for CVD due to abnormal lipids with total cholesterol ≥180 mg/dL and high-density lipoprotein (HDL) <60 mg/dL; low-density lipoprotein (LDL) ≥100 mg/dL and HDL <60 mg/dL; or non-HDL >100 mg/dL and HDL <60 mg/dL.


All children received muffins or a smoothie daily that included 0 g NBP or RB (control), 17.5 g NBP, 15 g RB, or a combination 9 g NBP + 8 g RB for 4 weeks.

According to the tested assays received from 38 children who completed the trial (n = 9 control, n = 10 NBP, n = 9 RB, and n = 10 NBP + RB groups),
* Participants in the intervention groups showed a significantly increased intake of NBP and RB at week 4.

* Furthermore, the NBP and NBP + RB groups increased total fiber intake from baseline to week 4 (p=.02 and p=<.01, respectively).


* The levels of HDL-cholesterol were higher in NBP-group participants compared to control at week 4.


The results strongly suggested that navy beans exerted a significant effect on the improvement of blood cholesterol by increasing the serum of HLD in the blood which plays a critical role to lower the total cholesterol and return the bad cholesterol to the liver in the 4-week duration.

Dr. Borresen EC, the lead scientist, after taking other factors into account wrote, "Increasing NBP and/or RB intake is tolerable for children, and our findings suggest higher daily intakes are needed for a longer duration to induce favorable changes across multiple serum lipid parameters".

Taken altogether, the navy bean may be considered a remedy for the prevention and treatment of hypercholesterolemia, pending to the confirmation of the larger sample size and multicenter human study.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) A Pilot Randomized Controlled Clinical Trial to Assess Tolerance and Efficacy of Navy Bean and Rice Bran Supplementation for Lowering Cholesterol in Children by Borresen EC1, Jenkins-Puccetti N2, Schmitz K1, Brown DG1, Pollack A2, Fairbanks A1, Wdowik M1, Rao S1, Nelson TL1, Luckasen G3, Ryan EP. (PubMed)
(2) Age-Related Hypercholesterolemia and HMG-CoA Reductase Dysregulation: Sex Does Matter (A Gender Perspective) by Laura Trapani and Valentina Pallottini. (Hindawi)