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Saturday, April 19, 2014

Herbal Green Tea and Skin Aging

  Posted by Chantel Martiromo 

Skin aging is one of most visible process which occurs constantly in our skin organ. According to the Clinical Centre of Nis, certain plant extracts may have the ability to scavenge free radicals, to protect the skin matrix through the inhibition of enzymatic degradation, or to promote collagen synthesis in the skin,  affected skin elasticity and tightness(a). Other suggested that free radicals induced domino effects in production of reactive oxygen species, can react with DNA, proteins, and fatty acids, causing oxidative damage and impairment of antioxidant system, leading  injuries damage regulation pathways of skin,  including wrinkles, roughness, appearance of fine lines, lack of elasticity, and de- or hyperpigmentation marks(b).
The degradation of the epidermal and dermal layers of the extracellular matrix (ECM), the non-cellular component present within all tissues and organs, such as UV Exposure, decline of lysosomal/endosomal cathepsin K, S and V activity(c) as well as some environmental factors on skin produces visible signs such as irregular dryness, dark/light pigmentation, sallowness, severe atrophy, telangiectases, premalignant lesions, laxity, leathery appearance and deep wrinkling, etc.,  cause modification of the surface of skin and the physical properties of that lead to skin aging.
Certain chemical ingredients, such as aloin, ginsenoside, curcumin, epicatechin, asiaticoside, ziyuglycoside I, magnolol, gallic acid, hydroxychavicol, hydroxycinnamic acids, hydroxybenzoic acids, etc.  derived from herbs have been found to be intergraded  into some cosmetic products in treating premature aging(d)
Green tea containing  more amount of antioxidants than any drinks or food with the same volume, is the leaves of Camellia sinensis, undergone minimal oxidation during processing, originated from China. Green tea has been a precious drink in traditional Chinese culture and used exceptional in socialization for more than 4000 thousand years. Because of their health benefits, they have been cultivated for commercial purposes all over the world.
Oxidative damage by reactive oxygen species (ROS) plays a major role in skin aging. Green tea extracted showed to inhibit the toxic ROS-induced skin death, through protection from H(2)O(2)-induced necrosis in a dose-dependent manner(4)(4a), improvement of the anti-wrinkle effects, through its antioxidant activity(5),  skin roughness, through moisturizing effects and enhancement of skin microrelief(6) and inhibition of skin inflammation for managing allergic contact dermatitis without skin toxicity(7). Combination of topical application of green tea and lotus, exhibited an anti aging effect on skin roughness (SEr), scaliness (SEsc), smoothness (SEsm), and wrinkling (SEw)(8) and  composition of a formulation containing 20 % green tea extract and 5 % rose oil, exhibited a skin barrier function for maintaining skin hydration, and protecting against anti-aging process(9).
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References
(a) Skin ageing: natural weapons and strategies by Binic I1, Lazarevic V, Ljubenovic M, Mojsa J, Sokolovic D.(PubMed)
(b) Phytoconstituents as photoprotective novel cosmetic formulations by Saraf S1, Kaur CD.(PubMed)
(c) Differential expression of cathepsins K, S and V between young and aged Caucasian women skin epidermis by Sage J1, De Quéral D2, Leblanc-Noblesse E2, Kurfurst R2, Schnebert S2, Perrier E2, Nizard C2, Lalmanach G3, Lecaille F4.(PubMed)
(d) Bioactive compounds from natural resources against skin aging by Mukherjee PK1, Maity N, Nema NK, Sarkar BK.(PubMed)
(4) Green tea extract protects human skin fibroblasts from reactive oxygen species induced necrosis by Silverberg JI1, Jagdeo J, Patel M, Siegel D, Brody N.(PubMed)
(5) Tannase-converted green tea catechins and their anti-wrinkle activity in humans by Hong YH1, Jung EY, Shin KS, Yu KW, Chang UJ, Suh HJ.(PubMed)
(6) The use of green tea extract in cosmetic formulations: not only an antioxidant active ingredient by Gianeti MD1, Mercurio DG, Campos PM.(PubMed)
(7) Human skin safety test of green tea cell extracts in condition of allergic contact dermatitis by Kim HK1, Choi SY, Chang HK, Baek SY, Chung JO, Rha CS, Kim BJ, Kim MN.(PubMed)
(8) Combined topical application of lotus and green tea improves facial skin surface parameters by Mahmood T1, Akhtar N.(PubMed)
(9) Design and in vivo evaluation of emulgel formulations including green tea extract and rose oil by Yapar EA, Ynal O, Erdal MS.(PubMed)

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