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Wednesday, April 2, 2014

Ovarian Cancer and Herbal Lingzhi (LZ)

  Posted by Chantel Martiromo

Ovarian cancer is defined as a condition of  abnormal ovarian cells growth of ovaries.  It is one of most common cancer in US, according to the statistics adapted from the American Cancer Society's publication, Cancer Facts & Figures 2010, an estimated 21,880 women in the United States will be diagnosed with ovarian cancer and 13,850 deaths.

Ling Zhi is also known as Lucid Ganoderma. The sweet and netral herb has been used in TCM to treat cough, asthma, tinnitus, deafness and lassitude of the loins and knees, palpitation, insomnia and amnesia, hepatitis B, etc. as it nourishes Yin and Blood, strengthens the Spleen tonifies Qi and Body Fluids, calms the Mind, strengthens the Stomach, etc., by enhancing the functions of Lung, Kidney, Liver, Heart, Spleen and Stomach channels.
Lingzhi (LZ),  also known as Ganoderma lucidum, inhibited the ovarian cancer cell line OVCAR-3, through  suppressing cell growth and inducing antioxidative/detoxification activity(16). Other study suggested that LingZhi also strongly decreased cell numbers in a dose-dependent manner. through inhibition of colony formation, cell migration and spheroid formation(17).  
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References  

(16) Suppression of proliferation and oxidative stress by extracts of Ganoderma lucidum in the ovarian cancer cell line OVCAR-3 by Hsieh TC1, Wu JM.(PubMed)
(17) Ganoderma lucidum exerts anti-tumor effects on ovarian cancer cells and enhances their sensitivity to cisplatin by Zhao S1, Ye G, Fu G, Cheng JX, Yang BB, Peng C.(PubMed
 

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