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Friday, April 4, 2014

Ovarian Cancer and Rosemary

  Posted by Chantel Martiromo

Ovarian cancer is defined as a condition of  abnormal ovarian cells growth of ovaries.  It is one of most common cancer in US, according to the statistics adapted from the American Cancer Society's publication, Cancer Facts & Figures 2010, an estimated 21,880 women in the United States will be diagnosed with ovarian cancer and 13,850 deaths.
Rosemary is a perennial herb with fragrant, evergreen, needle-like leaves, the genus Rosmarinus, belonging to the family Lamiaceae. Its fresh and dried leaves has been used frequently in traditional Mediterranean cuisine and as flavor foods while barbecuing. Rosnary has been used in traditional medicine as an antiseptic, antioxidant, and antispasmodic agent to treat circulatory problem, eczema, rheumatism, muscle pain, etc.
Crude extracts of rosemary (Rosmarinus officinalis L), has been found to consist anti-proliferative property on several human cancer cell lines and antioxidant and anti-inflammatory properties(20).
Carnosol (CS), carnosic acid (CA) and rosmarinic acid (RA), the main ingredients in rosemary extract, exhibited the significant antiproliferation activity on human ovarian cancer A2780 and its CDDP resistant daughter cell line A2780CP70, with IC(50) (50% inhibitory concentration)(21).
 
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References 

(20) Anti-proliferative and antioxidant properties of rosemary Rosmarinus officinalis.by Cheung S1, Tai J.(PubMed)
(21) Antiproliferation effect of Rosemary (Rosmarinus officinalis) on human ovarian cancer cells in vitro by Tai J1, Cheung S, Wu M, Hasman D.(PubMed)

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