Posted by Chantel Martiromo
Cervical cancer is malignant neoplasm of the cervix uteri
or cervical area caused by abnormal cells growth with alternation of
cells DNA. According to the American Cancer Society's, in 2014, 12,360
new cases of invasive cervical cancer will be diagnosed with the death
of 4,020 patients. The risk of cervical cancer is higher in Hispanic
women followed by African-Americans, Asians and Pacific Islanders, and
whites(a).
Depending to the stage and grade of the cancer, if the cancer is found
in the early stahe, hysterectomy may not be needed. Other while after
sugery, chemotherapy including Cisplatin, Fluorouracil (5-FU),
Mitomycin, Paclitaxel, Ifosfamide, Carboplatin, Bevacizumab and
radiotherapy may be necesary, but with certain side effects. Emerging
suggestion of a healthy and balanced diet to improve high serum levels of antioxidants may reduce cervical neoplasia risk(b)(c) but other suggested that the role of diet and nutrition in the etiology of cervical cancer
is not yet resolved(d) and Catalan Institute of Oncology study showed
statistically nonsignificant inverse associations were also observed for
leafy vegetables, root vegetables, garlic and onions, citrus fruits, vitamin C, vitamin E and retinol for invasive squamous cervical cancer (ISC)(e).
Cruciferous vegetables are the group of
vegetables belonging to the family Brassicaceae, including
cauliflower, cabbage, cress, bok choy, broccoli etc.
Isothiocyanates, a major chemical constituent found in Cruciferous vegetables, inhibited the cell viability of human cervical cancer
cells, through improvement of antioxidant status(1). β-Phenylethyl
isothiocyanate (PEITC). induced apoptosis to inhibit cell proliferation
in human cervical cancer cell lines
(HEp-2 and KB), through increased the expression of the death receptors
(DR4 and DR5) and cleaved caspase-3(2). Other chemical compounds, I3C
(indole-3-carbinol) and DIM (diindolylmethane) found in all types of cruciferous vegetables, demonstrated exceptional anti-cancer effects against hormone responsive cancers such as ovarian cancers(3). Some researchers suggested that isothiocyanates and indoles through intake of cruciferous vegetable may decrease cancer
risk, but the protective effects may be influenced by individual
genetic variation (polymorphisms) in the metabolism and elimination of
isothiocyanates from the body and in some in instances, long term
exposure to sulforaphane and indole-3-carbinol (I3C), may be implicated
in a variety of anticarcinogenic mechanisms(4).
Chinese Secrets to Fatty Liver and Obesity Reversal
A
Ovarian Cysts And PCOS Elimination
Back to Tofu and 600+ healthy recipe http://thetruestoriesstories.blogspot.ca/p/soy-recipes.html
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References
(a) Cerical cancer (Amerrican cancer society)
(b) Diet and serum micronutrients in relation to cervical neoplasia and cancer among low-income Brazilian women by Tomita LY1, Longatto Filho A, Costa MC, Andreoli MA, Villa LL, Franco EL, Cardoso MA; Brazilian Investigation into Nutrition and Cervical Cancer Prevention (BRINCA) Study Team.(PubMed)
(c) Associations of dietary dark-green and deep-yellow vegetables and fruits with cervical intraepithelial neoplasia: modification by smoking by Tomita LY1, Roteli-Martins CM, Villa LL, Franco EL, Cardoso MA; BRINCA Study Team.(PubMed)
(d) Diet and the risk of in situ cervical cancer among white women in the United States by Ziegler RG1, Jones CJ, Brinton LA, Norman SA, Mallin K, Levine RS, Lehman HF, Hamman RF, Trumble AC, Rosenthal JF, et al.(PubMed)
(e) Dietary factors and in situ and invasive cervical cancer risk in the European prospective investigation into cancer and nutrition study by González CA1,
Travier N, Luján-Barroso L, Castellsagué X, Bosch FX, Roura E,
Bueno-de-Mesquita HB, Palli D, Boeing H, Pala V, Sacerdote C, Tumino R,
Panico S, Manjer J, Dillner J, Hallmans G, Kjellberg L, Sanchez MJ,
Altzibar JM, Barricarte A, Navarro C, Rodriguez L, Allen N, Key TJ,
Kaaks R, Rohrmann S, Overvad K, Olsen A, Tjønneland A, Munk C, Kjaer SK,
Peeters PH, van Duijnhoven FJ, Clavel-Chapelon F, Boutron-Ruault MC,
Trichopoulou A, Benetou V, Naska A, Lund E, Engeset D, Skeie G,
Franceschi S, Slimani N, Rinaldi S, Riboli E.(PubMed)
(1) The anti-oxidant properties of isothiocyanates: a review by de Figueiredo SM1, Filho SA, Nogueira-Machado JA, Caligiorne RB.(PubMed)
(2) Effect of β-phenylethyl isothiocyanate from cruciferous vegetables on growth inhibition and apoptosis of cervical cancer cells through the induction of death receptors 4 and 5 by Huong le D1, Shim JH, Choi KH, Shin JA, Choi ES, Kim HS, Lee SJ, Kim SJ, Cho NP, Cho SD(PubMed)
(3) Chemopreventive properties of indole-3-carbinol, diindolylmethane
and other constituents of cardamom against carcinogenesis by Acharya A1, Das I, Singh S, Saha T.(PubMed)
(4) Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis by Higdon JV1, Delage B, Williams DE, Dashwood RH.(PubMed)
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Saturday, May 31, 2014
Ranch Pretzel Bites
Posted by Chantel Martiromo
Recipe by Quick and easy family favorites (by Vickie and JoAnn)
This snack mix is a variation on one that uses oyster crackers. Whichever you use, eat up, because it won't last for long!
16-oz. pkg. large pretzels
2-oz. pkg. ranch salad dressing mix
3/4 c. oil
11/2 t. garlic powder
11/2 t, dill weed
Break pretzels into bite-size pieces; place in a large mixing bowl. Combined remaining ingredients in a separate mixing bowl and pour over pretzels; toss to coat, Pour into an ungreased baking sheet.
bake at 200 degrees for 1 hour, stirring every 15 minutes.
Make 16 serving
Note: small bite-size pretzels may be substituted for a large pretzels.
Susan Young
Madison, AL
Chinese Secrets to Fatty Liver and Obesity Reversal
A
Ovarian Cysts And PCOS Elimination
Back to Tofu and 600+ healthy recipe http://thetruestoriesstories.blogspot.ca/p/soy-recipes.html
Back to my Home page at http://thetruestoriesstories.blogspot.ca/
Recipe by Quick and easy family favorites (by Vickie and JoAnn)
This snack mix is a variation on one that uses oyster crackers. Whichever you use, eat up, because it won't last for long!
16-oz. pkg. large pretzels
2-oz. pkg. ranch salad dressing mix
3/4 c. oil
11/2 t. garlic powder
11/2 t, dill weed
Break pretzels into bite-size pieces; place in a large mixing bowl. Combined remaining ingredients in a separate mixing bowl and pour over pretzels; toss to coat, Pour into an ungreased baking sheet.
bake at 200 degrees for 1 hour, stirring every 15 minutes.
Make 16 serving
Note: small bite-size pretzels may be substituted for a large pretzels.
Susan Young
Madison, AL
Chinese Secrets to Fatty Liver and Obesity Reversal
A
Ovarian Cysts And PCOS Elimination
Back to Tofu and 600+ healthy recipe http://thetruestoriesstories.blogspot.ca/p/soy-recipes.html
Back to my Home page at http://thetruestoriesstories.blogspot.ca/
Friday, May 30, 2014
Milk Thistle and Cervical Cancer
Posted by Chantel Martiromo
Cervical cancer is malignant neoplasm of the cervix uteri or cervical area caused by abnormal cells growth with alternation of cells DNA. According to the American Cancer Society's, in 2014, 12,360 new cases of invasive cervical cancer will be diagnosed with the death of 4,020 patients. The risk of cervical cancer is higher in Hispanic women followed by African-Americans, Asians and Pacific Islanders, and whites(a).
Depending to the stage and grade of the cancer, if the cancer is found in the early stahe, hysterectomy may not be needed. Other while after sugery, chemotherapy including Cisplatin, Fluorouracil (5-FU), Mitomycin, Paclitaxel, Ifosfamide, Carboplatin, Bevacizumab and radiotherapy may be necesary, but with certain side effects. Emerging suggestion of a healthy and balanced diet to improve high serum levels of antioxidants may reduce cervical neoplasia risk(b)(c) but other suggested that the role of diet and nutrition in the etiology of cervical cancer is not yet resolved(d) and Catalan Institute of Oncology study showed statistically nonsignificant inverse associations were also observed for leafy vegetables, root vegetables, garlic and onions, citrus fruits, vitamin C, vitamin E and retinol for invasive squamous cervical cancer (ISC)(e).
Milk Thistle is a flowering plant, in the genus Silybum Adans, belonging to the family Asteraceae, native to the Mediterranean. The herb has been used in traditional medicine in treating liver, kidney, gall bladder problems, etc.
Silibinin, an active constituent extracted from milk thistle (Silybum marianum), exhibited the cytotoxicity of NO in HeLa cells, through induced GSH depletion mediated by p53(27). In cervical cancer cells (C-33A), silymarin inhibited cancer cell viability and induced apoptosis through the modulation of Bcl-2 family proteins and activation of caspase 3(28). Other study found that the chemical compound also exerted its anti proliferative effect of human cervical cell line (HeLa) through inhibition of hypoxia-induced HIF-1alpha accumulation and HIF-1 transcriptional activity in human cervical (HeLa)(29)
Chinese Secrets to Fatty Liver and Obesity Reversal
A
Ovarian Cysts And PCOS Elimination
Back to Tofu and 600+ healthy recipe http://thetruestoriesstories.blogspot.ca/p/soy-recipes.html
Back to my Home page at http://thetruestoriesstories.blogspot.ca/
References
(a) Cerical cancer (Amerrican cancer society)
(b) Diet and serum micronutrients in relation to cervical neoplasia and cancer among low-income Brazilian women by Tomita LY1, Longatto Filho A, Costa MC, Andreoli MA, Villa LL, Franco EL, Cardoso MA; Brazilian Investigation into Nutrition and Cervical Cancer Prevention (BRINCA) Study Team.(PubMed)
(c) Associations of dietary dark-green and deep-yellow vegetables and fruits with cervical intraepithelial neoplasia: modification by smoking by Tomita LY1, Roteli-Martins CM, Villa LL, Franco EL, Cardoso MA; BRINCA Study Team.(PubMed)
(d) Diet and the risk of in situ cervical cancer among white women in the United States by Ziegler RG1, Jones CJ, Brinton LA, Norman SA, Mallin K, Levine RS, Lehman HF, Hamman RF, Trumble AC, Rosenthal JF, et al.(PubMed)
(e) Dietary factors and in situ and invasive cervical cancer risk in the European prospective investigation into cancer and nutrition study by González CA1, Travier N, Luján-Barroso L, Castellsagué X, Bosch FX, Roura E, Bueno-de-Mesquita HB, Palli D, Boeing H, Pala V, Sacerdote C, Tumino R, Panico S, Manjer J, Dillner J, Hallmans G, Kjellberg L, Sanchez MJ, Altzibar JM, Barricarte A, Navarro C, Rodriguez L, Allen N, Key TJ, Kaaks R, Rohrmann S, Overvad K, Olsen A, Tjønneland A, Munk C, Kjaer SK, Peeters PH, van Duijnhoven FJ, Clavel-Chapelon F, Boutron-Ruault MC, Trichopoulou A, Benetou V, Naska A, Lund E, Engeset D, Skeie G, Franceschi S, Slimani N, Rinaldi S, Riboli E.(PubMed)
(27) P53-mediated GSH depletion enhanced the cytotoxicity of NO in silibinin-treated human cervical carcinoma HeLa cells by Fan S1, Yu Y, Qi M, Sun Z, Li L, Yao G, Tashiro S, Onodera S, Ikejima T.(PubMed)
(28) Silymarin inhibits cervical cancer cell through an increase of phosphatase and tensin homolog by Yu HC1, Chen LJ, Cheng KC, Li YX, Yeh CH, Cheng JT.(PubMed)
(29) Silibinin inhibits hypoxia-inducible factor-1alpha and mTOR/p70S6K/4E-BP1 signalling pathway in human cervical and hepatoma cancer cells: implications for anticancer therapy by García-Maceira P1, Mateo J.(PubMed)
Cervical cancer is malignant neoplasm of the cervix uteri or cervical area caused by abnormal cells growth with alternation of cells DNA. According to the American Cancer Society's, in 2014, 12,360 new cases of invasive cervical cancer will be diagnosed with the death of 4,020 patients. The risk of cervical cancer is higher in Hispanic women followed by African-Americans, Asians and Pacific Islanders, and whites(a).
Depending to the stage and grade of the cancer, if the cancer is found in the early stahe, hysterectomy may not be needed. Other while after sugery, chemotherapy including Cisplatin, Fluorouracil (5-FU), Mitomycin, Paclitaxel, Ifosfamide, Carboplatin, Bevacizumab and radiotherapy may be necesary, but with certain side effects. Emerging suggestion of a healthy and balanced diet to improve high serum levels of antioxidants may reduce cervical neoplasia risk(b)(c) but other suggested that the role of diet and nutrition in the etiology of cervical cancer is not yet resolved(d) and Catalan Institute of Oncology study showed statistically nonsignificant inverse associations were also observed for leafy vegetables, root vegetables, garlic and onions, citrus fruits, vitamin C, vitamin E and retinol for invasive squamous cervical cancer (ISC)(e).
Milk Thistle is a flowering plant, in the genus Silybum Adans, belonging to the family Asteraceae, native to the Mediterranean. The herb has been used in traditional medicine in treating liver, kidney, gall bladder problems, etc.
Silibinin, an active constituent extracted from milk thistle (Silybum marianum), exhibited the cytotoxicity of NO in HeLa cells, through induced GSH depletion mediated by p53(27). In cervical cancer cells (C-33A), silymarin inhibited cancer cell viability and induced apoptosis through the modulation of Bcl-2 family proteins and activation of caspase 3(28). Other study found that the chemical compound also exerted its anti proliferative effect of human cervical cell line (HeLa) through inhibition of hypoxia-induced HIF-1alpha accumulation and HIF-1 transcriptional activity in human cervical (HeLa)(29)
Chinese Secrets to Fatty Liver and Obesity Reversal
A
Ovarian Cysts And PCOS Elimination
Back to Tofu and 600+ healthy recipe http://thetruestoriesstories.blogspot.ca/p/soy-recipes.html
Back to my Home page at http://thetruestoriesstories.blogspot.ca/
References
(a) Cerical cancer (Amerrican cancer society)
(b) Diet and serum micronutrients in relation to cervical neoplasia and cancer among low-income Brazilian women by Tomita LY1, Longatto Filho A, Costa MC, Andreoli MA, Villa LL, Franco EL, Cardoso MA; Brazilian Investigation into Nutrition and Cervical Cancer Prevention (BRINCA) Study Team.(PubMed)
(c) Associations of dietary dark-green and deep-yellow vegetables and fruits with cervical intraepithelial neoplasia: modification by smoking by Tomita LY1, Roteli-Martins CM, Villa LL, Franco EL, Cardoso MA; BRINCA Study Team.(PubMed)
(d) Diet and the risk of in situ cervical cancer among white women in the United States by Ziegler RG1, Jones CJ, Brinton LA, Norman SA, Mallin K, Levine RS, Lehman HF, Hamman RF, Trumble AC, Rosenthal JF, et al.(PubMed)
(e) Dietary factors and in situ and invasive cervical cancer risk in the European prospective investigation into cancer and nutrition study by González CA1, Travier N, Luján-Barroso L, Castellsagué X, Bosch FX, Roura E, Bueno-de-Mesquita HB, Palli D, Boeing H, Pala V, Sacerdote C, Tumino R, Panico S, Manjer J, Dillner J, Hallmans G, Kjellberg L, Sanchez MJ, Altzibar JM, Barricarte A, Navarro C, Rodriguez L, Allen N, Key TJ, Kaaks R, Rohrmann S, Overvad K, Olsen A, Tjønneland A, Munk C, Kjaer SK, Peeters PH, van Duijnhoven FJ, Clavel-Chapelon F, Boutron-Ruault MC, Trichopoulou A, Benetou V, Naska A, Lund E, Engeset D, Skeie G, Franceschi S, Slimani N, Rinaldi S, Riboli E.(PubMed)
(27) P53-mediated GSH depletion enhanced the cytotoxicity of NO in silibinin-treated human cervical carcinoma HeLa cells by Fan S1, Yu Y, Qi M, Sun Z, Li L, Yao G, Tashiro S, Onodera S, Ikejima T.(PubMed)
(28) Silymarin inhibits cervical cancer cell through an increase of phosphatase and tensin homolog by Yu HC1, Chen LJ, Cheng KC, Li YX, Yeh CH, Cheng JT.(PubMed)
(29) Silibinin inhibits hypoxia-inducible factor-1alpha and mTOR/p70S6K/4E-BP1 signalling pathway in human cervical and hepatoma cancer cells: implications for anticancer therapy by García-Maceira P1, Mateo J.(PubMed)
Cheese bread Bites
Posted by Chantel Martiromo
Recipe by Quick and easy family favorites (by Vickie and JoAnn)
Make up of this double patch of these yummy bites to have on hand for unexpected company.... or for yourself for snacking! They're handy snack, because you can bake just a few at a time when you want them.
12-oz loaf French bread, crust trimmed
1 c. butter
1/2 lb. sharp Cheddar cheese cubed
2(3-oz.) pkgs. cream cheese soften
4 eggs whites stiffly beaten
Optional: marinara sauce
Cut bread into 1 inch cubes; set aside. Melt butter and cheeses in a double boiler over low heat, stirring often. Remove from heat; fold in egg whites. Dip bread cubes into cheese mixture; set on greased baking sheets. Place into freezer until frozen: remove from baking sheets and store in plastic zipping bags in the freezer up to one month.
To serve, bake frozen bites at 400 degrees for 12 minutes on greased baking sheets. Serve with marinara sauce, if desired.
Serve 8 to 10.
Chinese Secrets to Fatty Liver and Obesity Reversal
A
Ovarian Cysts And PCOS Elimination
Back to Tofu and 600+ healthy recipe http://thetruestoriesstories.blogspot.ca/p/soy-recipes.html
Back to my Home page at http://thetruestoriesstories.blogspot.ca/
Recipe by Quick and easy family favorites (by Vickie and JoAnn)
Make up of this double patch of these yummy bites to have on hand for unexpected company.... or for yourself for snacking! They're handy snack, because you can bake just a few at a time when you want them.
12-oz loaf French bread, crust trimmed
1 c. butter
1/2 lb. sharp Cheddar cheese cubed
2(3-oz.) pkgs. cream cheese soften
4 eggs whites stiffly beaten
Optional: marinara sauce
Cut bread into 1 inch cubes; set aside. Melt butter and cheeses in a double boiler over low heat, stirring often. Remove from heat; fold in egg whites. Dip bread cubes into cheese mixture; set on greased baking sheets. Place into freezer until frozen: remove from baking sheets and store in plastic zipping bags in the freezer up to one month.
To serve, bake frozen bites at 400 degrees for 12 minutes on greased baking sheets. Serve with marinara sauce, if desired.
Serve 8 to 10.
Chinese Secrets to Fatty Liver and Obesity Reversal
A
Ovarian Cysts And PCOS Elimination
Back to Tofu and 600+ healthy recipe http://thetruestoriesstories.blogspot.ca/p/soy-recipes.html
Back to my Home page at http://thetruestoriesstories.blogspot.ca/
Thursday, May 29, 2014
Ginseng and Cervical Cancer
Posted by Chantel Martiromo
Cervical cancer is malignant neoplasm of the cervix uteri or cervical area caused by abnormal cells growth with alternation of cells DNA. According to the American Cancer Society's, in 2014, 12,360 new cases of invasive cervical cancer will be diagnosed with the death of 4,020 patients. The risk of cervical cancer is higher in Hispanic women followed by African-Americans, Asians and Pacific Islanders, and whites(a).
Depending to the stage and grade of the cancer, if the cancer is found in the early stahe, hysterectomy may not be needed. Other while after sugery, chemotherapy including Cisplatin, Fluorouracil (5-FU), Mitomycin, Paclitaxel, Ifosfamide, Carboplatin, Bevacizumab and radiotherapy may be necesary, but with certain side effects. Emerging suggestion of a healthy and balanced diet to improve high serum levels of antioxidants may reduce cervical neoplasia risk(b)(c) but other suggested that the role of diet and nutrition in the etiology of cervical cancer is not yet resolved(d) and Catalan Institute of Oncology study showed statistically nonsignificant inverse associations were also observed for leafy vegetables, root vegetables, garlic and onions, citrus fruits, vitamin C, vitamin E and retinol for invasive squamous cervical cancer (ISC)(e).
Epidemiological studies, linking herbal medicine in reduced risk of cervical cancer have not been consistent. But certain herbs and spice may be effective in treating cervical caner(1) with little or no side effects.
Ginseng is a slow-growing perennial plants with fleshy roots, the genus Panax, belonging to the family Araliaceae. Depending to the climate where it grows, ginseng can be classified mainly into Panax ginseng Asian ginseng (root), Red ginseng, wild ginseng, American ginseng (root).
Ginsenosides, the major chemical composition of Panax ginseng inhibited 74% human cervical cancer cells (Hela) after 72 h exposure(25). Saponin ginsenoside Rd (1), isolated from Panax notoginseng inhibited HeLa cell proliferation, and induced cell apoptosis through down-regulating Bcl-2 expression, up-regulating Bax expression, lowering the mitochondrial transmembrane potential, and activating the caspase-3 pathway(26).
Chinese Secrets to Fatty Liver and Obesity Reversal
A
Ovarian Cysts And PCOS Elimination
Back to Tofu and 600+ healthy recipe http://thetruestoriesstories.blogspot.ca/p/soy-recipes.html
Back to my Home page at http://thetruestoriesstories.blogspot.ca/
References
(a) Cerical cancer (Amerrican cancer society)
(b) Diet and serum micronutrients in relation to cervical neoplasia and cancer among low-income Brazilian women by Tomita LY1, Longatto Filho A, Costa MC, Andreoli MA, Villa LL, Franco EL, Cardoso MA; Brazilian Investigation into Nutrition and Cervical Cancer Prevention (BRINCA) Study Team.(PubMed)
(c) Associations of dietary dark-green and deep-yellow vegetables and fruits with cervical intraepithelial neoplasia: modification by smoking by Tomita LY1, Roteli-Martins CM, Villa LL, Franco EL, Cardoso MA; BRINCA Study Team.(PubMed)
(d) Diet and the risk of in situ cervical cancer among white women in the United States by Ziegler RG1, Jones CJ, Brinton LA, Norman SA, Mallin K, Levine RS, Lehman HF, Hamman RF, Trumble AC, Rosenthal JF, et al.(PubMed)
(e) Dietary factors and in situ and invasive cervical cancer risk in the European prospective investigation into cancer and nutrition study by González CA1, Travier N, Luján-Barroso L, Castellsagué X, Bosch FX, Roura E, Bueno-de-Mesquita HB, Palli D, Boeing H, Pala V, Sacerdote C, Tumino R, Panico S, Manjer J, Dillner J, Hallmans G, Kjellberg L, Sanchez MJ, Altzibar JM, Barricarte A, Navarro C, Rodriguez L, Allen N, Key TJ, Kaaks R, Rohrmann S, Overvad K, Olsen A, Tjønneland A, Munk C, Kjaer SK, Peeters PH, van Duijnhoven FJ, Clavel-Chapelon F, Boutron-Ruault MC, Trichopoulou A, Benetou V, Naska A, Lund E, Engeset D, Skeie G, Franceschi S, Slimani N, Rinaldi S, Riboli E.(PubMed)
(25) Ginsenosides extracted from nanoscale Chinese white ginseng enhances anticancer effect by Ji Y1, Rao Z, Cui J, Bao H, Chen C, Shu C, Gong JR(PubMed)
(26) Ginsenoside Rd from Panax notoginseng is cytotoxic towards HeLa cancer cells and induces apoptosis by Yang ZG1, Sun HX, Ye YP.(PubMed)
Cervical cancer is malignant neoplasm of the cervix uteri or cervical area caused by abnormal cells growth with alternation of cells DNA. According to the American Cancer Society's, in 2014, 12,360 new cases of invasive cervical cancer will be diagnosed with the death of 4,020 patients. The risk of cervical cancer is higher in Hispanic women followed by African-Americans, Asians and Pacific Islanders, and whites(a).
Depending to the stage and grade of the cancer, if the cancer is found in the early stahe, hysterectomy may not be needed. Other while after sugery, chemotherapy including Cisplatin, Fluorouracil (5-FU), Mitomycin, Paclitaxel, Ifosfamide, Carboplatin, Bevacizumab and radiotherapy may be necesary, but with certain side effects. Emerging suggestion of a healthy and balanced diet to improve high serum levels of antioxidants may reduce cervical neoplasia risk(b)(c) but other suggested that the role of diet and nutrition in the etiology of cervical cancer is not yet resolved(d) and Catalan Institute of Oncology study showed statistically nonsignificant inverse associations were also observed for leafy vegetables, root vegetables, garlic and onions, citrus fruits, vitamin C, vitamin E and retinol for invasive squamous cervical cancer (ISC)(e).
Epidemiological studies, linking herbal medicine in reduced risk of cervical cancer have not been consistent. But certain herbs and spice may be effective in treating cervical caner(1) with little or no side effects.
Ginseng is a slow-growing perennial plants with fleshy roots, the genus Panax, belonging to the family Araliaceae. Depending to the climate where it grows, ginseng can be classified mainly into Panax ginseng Asian ginseng (root), Red ginseng, wild ginseng, American ginseng (root).
Ginsenosides, the major chemical composition of Panax ginseng inhibited 74% human cervical cancer cells (Hela) after 72 h exposure(25). Saponin ginsenoside Rd (1), isolated from Panax notoginseng inhibited HeLa cell proliferation, and induced cell apoptosis through down-regulating Bcl-2 expression, up-regulating Bax expression, lowering the mitochondrial transmembrane potential, and activating the caspase-3 pathway(26).
Chinese Secrets to Fatty Liver and Obesity Reversal
A
Ovarian Cysts And PCOS Elimination
Back to Tofu and 600+ healthy recipe http://thetruestoriesstories.blogspot.ca/p/soy-recipes.html
Back to my Home page at http://thetruestoriesstories.blogspot.ca/
References
(a) Cerical cancer (Amerrican cancer society)
(b) Diet and serum micronutrients in relation to cervical neoplasia and cancer among low-income Brazilian women by Tomita LY1, Longatto Filho A, Costa MC, Andreoli MA, Villa LL, Franco EL, Cardoso MA; Brazilian Investigation into Nutrition and Cervical Cancer Prevention (BRINCA) Study Team.(PubMed)
(c) Associations of dietary dark-green and deep-yellow vegetables and fruits with cervical intraepithelial neoplasia: modification by smoking by Tomita LY1, Roteli-Martins CM, Villa LL, Franco EL, Cardoso MA; BRINCA Study Team.(PubMed)
(d) Diet and the risk of in situ cervical cancer among white women in the United States by Ziegler RG1, Jones CJ, Brinton LA, Norman SA, Mallin K, Levine RS, Lehman HF, Hamman RF, Trumble AC, Rosenthal JF, et al.(PubMed)
(e) Dietary factors and in situ and invasive cervical cancer risk in the European prospective investigation into cancer and nutrition study by González CA1, Travier N, Luján-Barroso L, Castellsagué X, Bosch FX, Roura E, Bueno-de-Mesquita HB, Palli D, Boeing H, Pala V, Sacerdote C, Tumino R, Panico S, Manjer J, Dillner J, Hallmans G, Kjellberg L, Sanchez MJ, Altzibar JM, Barricarte A, Navarro C, Rodriguez L, Allen N, Key TJ, Kaaks R, Rohrmann S, Overvad K, Olsen A, Tjønneland A, Munk C, Kjaer SK, Peeters PH, van Duijnhoven FJ, Clavel-Chapelon F, Boutron-Ruault MC, Trichopoulou A, Benetou V, Naska A, Lund E, Engeset D, Skeie G, Franceschi S, Slimani N, Rinaldi S, Riboli E.(PubMed)
(25) Ginsenosides extracted from nanoscale Chinese white ginseng enhances anticancer effect by Ji Y1, Rao Z, Cui J, Bao H, Chen C, Shu C, Gong JR(PubMed)
(26) Ginsenoside Rd from Panax notoginseng is cytotoxic towards HeLa cancer cells and induces apoptosis by Yang ZG1, Sun HX, Ye YP.(PubMed)
The antioxidants and Skin Lightening (Whitening)
Human skin pigmentation is the result of natural selection evolved to
prevent damage to skin through regulation of ultraviolet radiated
penetration depending to the production of melanin in the skin cells.
1. Hypo-pigment
a. Vitiligo is defined as a condition of destruction of cells that give your skin its color, causing white patches on your skin.
b. Albinism is a congenital disorder causes of complete or partial absence of pigment in the skin, hair and eyes as a result of restriction of the skin cells from producing melanin
2.Hyper pigment is a result of over production of pigments of certain cells in the skin, causing skin darkening in some area, such as tan or brown patches, commonly on the facial skin
3. Skin discoloring is a result of discoloring your skin in specific spots or very widespread
4. Chloasma is the appearance of brown patches of pigmentation on the forehead, cheeks, and neck
due to hormonal change during pregnancy.
5. Melasma happens to women who have fluctuation of hormones, are taking birth control pills and certain medications. with brownish-grayish patches on the skin, most often on the cheek.
Epidemiological studies, linking herbal medicine in skin lighting may have produced certain interest results(a)(b)(c).
The antioxidants
1. Resveratrol
Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in skins and seed of grape wine, nuts, peanuts, etc.
Piceatannol, a derivative of resveratrol exerted its antimelanogenic action through the combined effect of antioxidative property
and suppressed RS generation while increasing the GSH/GSSG ratio(30). According to 1Johnson &
Johnson Skin Research Center, resveratrol may be a potential cosmetic skin whitening agent through
reduced microphthalmia-associated transcription factor and tyrosinase promoter activities(31).
4. Glutathione
Glutathione (GSH), an antioxidants plays an important role in protecting cells against the free radicals
and ixidative stress, may be a potential agent in the management of hyperpigmentation(32). According
to the Chulalongkorn University, orally administered glutathione, 500 mg per day for 4 weeks, was found
effectively in reduced melanin indices consistently in all subjects(33) and may be used in the treatment
of pigmentary disorders.(34). Other study also indicated the effectiveness of glutathione in regulating
melanocytotoxicity and depigmenting potency of N-acetyl-4-S-CAP in black and yellow mice(35)
Chinese Secrets to Fatty Liver and Obesity Reversal
A
Ovarian Cysts And PCOS Elimination
Back to Tofu and 600+ healthy recipe http://thetruestoriesstories.blogspot.ca/p/soy-recipes.html
Back to my Home page at http://thetruestoriesstories.blogspot.ca/
References
(a) Tyrosinase modulation by five Rwandese herbal medicines traditionally used for skin treatment by Kamagaju L1, Morandini R, Bizuru E, Nyetera P, Nduwayezu JB, Stévigny C, Ghanem G, Duez P.(PubMed)
(b) An ethnobotanical survey of medicinal plants used in Rwanda for voluntary depigmentation by Kamagaju L1, Bizuru E, Minani V, Morandini R, Stévigny C, Ghanem G, Duez P.(PubMed)
(c) Tyrosinase inhibition by extracts and constituents of Sideroxylon inerme L. stem bark, used in South Africa for skin lightening by Momtaz S1, Mapunya BM, Houghton PJ, Edgerly C, Hussein A, Naidoo S, Lall N.(PubMed))
(31) Modulation of microphthalmia-associated transcription factor gene expression alters skin pigmentation by Lin CB1, Babiarz L, Liebel F, Roydon Price E, Kizoulis M, Gendimenico GJ, Fisher DE, Seiberg M.(PubMed)
(32) Natural ingredients for darker skin types: growing options for hyperpigmentation by Alexis AF Blackcloud P.(PubMed)
(33) Glutathione as an oral whitening agent: a randomized, double-blind, placebo-controlled study by Arjinpathana N1, Asawanonda P.(PubMed)
(34) Glutathione as a depigmenting agent: an overview by Villarama CD1, Maibach HI.(PubMed)
(35) Glutathione plays a key role in the depigmenting and melanocytotoxic action of N-acetyl-4-S-cysteaminylphenol in black and yellow hair follicles by Alena F1, Dixon W, Thomas P, Jimbow K.(PubMed)
1. Hypo-pigment
a. Vitiligo is defined as a condition of destruction of cells that give your skin its color, causing white patches on your skin.
b. Albinism is a congenital disorder causes of complete or partial absence of pigment in the skin, hair and eyes as a result of restriction of the skin cells from producing melanin
2.Hyper pigment is a result of over production of pigments of certain cells in the skin, causing skin darkening in some area, such as tan or brown patches, commonly on the facial skin
3. Skin discoloring is a result of discoloring your skin in specific spots or very widespread
4. Chloasma is the appearance of brown patches of pigmentation on the forehead, cheeks, and neck
due to hormonal change during pregnancy.
5. Melasma happens to women who have fluctuation of hormones, are taking birth control pills and certain medications. with brownish-grayish patches on the skin, most often on the cheek.
Epidemiological studies, linking herbal medicine in skin lighting may have produced certain interest results(a)(b)(c).
The antioxidants
1. Resveratrol
Resveratrol is a phytochemical in the class of Stilbenoids, found abundantly in skins and seed of grape wine, nuts, peanuts, etc.
Piceatannol, a derivative of resveratrol exerted its antimelanogenic action through the combined effect of antioxidative property
and suppressed RS generation while increasing the GSH/GSSG ratio(30). According to 1Johnson &
Johnson Skin Research Center, resveratrol may be a potential cosmetic skin whitening agent through
reduced microphthalmia-associated transcription factor and tyrosinase promoter activities(31).
4. Glutathione
Glutathione (GSH), an antioxidants plays an important role in protecting cells against the free radicals
and ixidative stress, may be a potential agent in the management of hyperpigmentation(32). According
to the Chulalongkorn University, orally administered glutathione, 500 mg per day for 4 weeks, was found
effectively in reduced melanin indices consistently in all subjects(33) and may be used in the treatment
of pigmentary disorders.(34). Other study also indicated the effectiveness of glutathione in regulating
melanocytotoxicity and depigmenting potency of N-acetyl-4-S-CAP in black and yellow mice(35)
Chinese Secrets to Fatty Liver and Obesity Reversal
A
Ovarian Cysts And PCOS Elimination
Back to Tofu and 600+ healthy recipe http://thetruestoriesstories.blogspot.ca/p/soy-recipes.html
Back to my Home page at http://thetruestoriesstories.blogspot.ca/
References
(a) Tyrosinase modulation by five Rwandese herbal medicines traditionally used for skin treatment by Kamagaju L1, Morandini R, Bizuru E, Nyetera P, Nduwayezu JB, Stévigny C, Ghanem G, Duez P.(PubMed)
(b) An ethnobotanical survey of medicinal plants used in Rwanda for voluntary depigmentation by Kamagaju L1, Bizuru E, Minani V, Morandini R, Stévigny C, Ghanem G, Duez P.(PubMed)
(c) Tyrosinase inhibition by extracts and constituents of Sideroxylon inerme L. stem bark, used in South Africa for skin lightening by Momtaz S1, Mapunya BM, Houghton PJ, Edgerly C, Hussein A, Naidoo S, Lall N.(PubMed))
(31) Modulation of microphthalmia-associated transcription factor gene expression alters skin pigmentation by Lin CB1, Babiarz L, Liebel F, Roydon Price E, Kizoulis M, Gendimenico GJ, Fisher DE, Seiberg M.(PubMed)
(32) Natural ingredients for darker skin types: growing options for hyperpigmentation by Alexis AF Blackcloud P.(PubMed)
(33) Glutathione as an oral whitening agent: a randomized, double-blind, placebo-controlled study by Arjinpathana N1, Asawanonda P.(PubMed)
(34) Glutathione as a depigmenting agent: an overview by Villarama CD1, Maibach HI.(PubMed)
(35) Glutathione plays a key role in the depigmenting and melanocytotoxic action of N-acetyl-4-S-cysteaminylphenol in black and yellow hair follicles by Alena F1, Dixon W, Thomas P, Jimbow K.(PubMed)
Crispy Parmesan Pita
Posted by Chantel Martiromo
Recipe by Quick and easy family favorites (by Vickie and JoAnn)
These is great salad and dips. For added flavor, sprinkle with garlic powder herbs before baking.
5 pita round
non-stick vegetable spray
1/2 c. grated Parmesan cheese
Split pitas and cut each half into wedges. Arrange on a baking sheet; spray lightly with non- stick vegetable spray and sprinkle with grated Parmesan. bake at 450 degrees for 8 to 10 minutes or until crisp.
make 5 dozen.
Laura Fuller
Fort Wayne, IN
Chinese Secrets to Fatty Liver and Obesity Reversal
A
Ovarian Cysts And PCOS Elimination
Back to Tofu and 600+ healthy recipe http://thetruestoriesstories.blogspot.ca/p/soy-recipes.html
Back to my Home page at http://thetruestoriesstories.blogspot.ca/
Recipe by Quick and easy family favorites (by Vickie and JoAnn)
These is great salad and dips. For added flavor, sprinkle with garlic powder herbs before baking.
5 pita round
non-stick vegetable spray
1/2 c. grated Parmesan cheese
Split pitas and cut each half into wedges. Arrange on a baking sheet; spray lightly with non- stick vegetable spray and sprinkle with grated Parmesan. bake at 450 degrees for 8 to 10 minutes or until crisp.
make 5 dozen.
Laura Fuller
Fort Wayne, IN
Chinese Secrets to Fatty Liver and Obesity Reversal
A
Ovarian Cysts And PCOS Elimination
Back to Tofu and 600+ healthy recipe http://thetruestoriesstories.blogspot.ca/p/soy-recipes.html
Back to my Home page at http://thetruestoriesstories.blogspot.ca/
Wednesday, May 28, 2014
Free radical scavengers Vitamin E and Skin Lightening (Whitening)
Posted by Chantel Martiromo
Human skin pigmentation is the result of natural selection evolved to prevent damage to skin through regulation of ultraviolet radiated penetration depending to the production of melanin in the skin cells.
1. Hypo-pigment
a. Vitiligo is defined as a condition of destruction of cells that give your skin its color, causing white patches on your skin.
b. Albinism is a congenital disorder causes of complete or partial absence of pigment in the skin, hair and eyes as a result of restriction of the skin cells from producing melanin
2.Hyper pigment is a result of over production of pigments of certain cells in the skin, causing skin darkening in some area, such as tan or brown patches, commonly on the facial skin
3. Skin discoloring is a result of discoloring your skin in specific spots or very widespread
4. Chloasma is the appearance of brown patches of pigmentation on the forehead, cheeks, and neck
due to hormonal change during pregnancy.
5. Melasma happens to women who have fluctuation of hormones, are taking birth control pills and certain medications. with brownish-grayish patches on the skin, most often on the cheek.
Free radical scavengers Vitamin E
Vitamin E, a fat soluble vitamin, consisting eight different variants (alpha-, beta-, gamma-, and delta-tocopherol and alpha-, beta-, gamma-, and delta-tocotrienol) with varying levels of biological activity(26), found abundantly in corn oil, soybean oil, margarine, wheat germ oil, sunflower,safflower oils, etc. plays an important role in neurological functions and inhibition of platelet aggregation, regulation of enzymatic activity, free radical scavenger, etc..
The study in comparison of the effects of vitamin E analogues (d-alpha-, dl-alpha-, d-beta-, d-gamma-, and d-delta-tocopherols, d-alpha- and dl-alpha-tocopheryl acetates) and 2,2,5,7,8-pentamethyl-6-hydroxychroman (PMC) on melanogenesis in mouse B16 melanoma cells, showed a positive effects of d-beta-tocopherol and d-gamma-tocopherol, 2 variants of vitamin E, in skin whitening with lower skin toxicity, as well as improved skin pigmentation such as skin spots and freckles caused by UV exposure(27). According to Kobe University School of Medicine, alpha-Tocopheryl ferulate (alpha-TF), a compound containing alpha-T (a variant of vitamin E) and ferulic acid exhibited an efficient whitening effects, through suppressed melanogenesis and inhibited biological reactions induced by reactive oxygen species(28)(29).
Chinese Secrets to Fatty Liver and Obesity Reversal
A
Ovarian Cysts And PCOS Elimination
Back to Tofu and 600+ healthy recipe http://thetruestoriesstories.blogspot.ca/p/soy-recipes.html
Back to my Home page at http://thetruestoriesstories.blogspot.ca/
References
(a) Tyrosinase modulation by five Rwandese herbal medicines traditionally used for skin treatment by Kamagaju L1, Morandini R, Bizuru E, Nyetera P, Nduwayezu JB, Stévigny C, Ghanem G, Duez P.(PubMed)
(b) An ethnobotanical survey of medicinal plants used in Rwanda for voluntary depigmentation by Kamagaju L1, Bizuru E, Minani V, Morandini R, Stévigny C, Ghanem G, Duez P.(PubMed)
(c) Tyrosinase inhibition by extracts and constituents of Sideroxylon inerme L. stem bark, used in South Africa for skin lightening by Momtaz S1, Mapunya BM, Houghton PJ, Edgerly C, Hussein A, Naidoo S, Lall N.(PubMed))
(27) Comparison of the inhibitory effects of vitamin E analogues on melanogenesis in mouse B16 melanoma cells by Kamei Y1, Otsuka Y, Abe K.(PubMed)
(28) The depigmenting effect of alpha-tocopheryl ferulate on human melanoma cells by Funasaka Y1, Chakraborty AK, Komoto M, Ohashi A, Ichihashi M.(PubMed)
(29) Depigmenting effect of alpha-tocopheryl ferulate on normal human melanocytes by Funasaka Y1, Komoto M, Ichihashi M.(PubMed)
Human skin pigmentation is the result of natural selection evolved to prevent damage to skin through regulation of ultraviolet radiated penetration depending to the production of melanin in the skin cells.
1. Hypo-pigment
a. Vitiligo is defined as a condition of destruction of cells that give your skin its color, causing white patches on your skin.
b. Albinism is a congenital disorder causes of complete or partial absence of pigment in the skin, hair and eyes as a result of restriction of the skin cells from producing melanin
2.Hyper pigment is a result of over production of pigments of certain cells in the skin, causing skin darkening in some area, such as tan or brown patches, commonly on the facial skin
3. Skin discoloring is a result of discoloring your skin in specific spots or very widespread
4. Chloasma is the appearance of brown patches of pigmentation on the forehead, cheeks, and neck
due to hormonal change during pregnancy.
5. Melasma happens to women who have fluctuation of hormones, are taking birth control pills and certain medications. with brownish-grayish patches on the skin, most often on the cheek.
Free radical scavengers Vitamin E
Vitamin E, a fat soluble vitamin, consisting eight different variants (alpha-, beta-, gamma-, and delta-tocopherol and alpha-, beta-, gamma-, and delta-tocotrienol) with varying levels of biological activity(26), found abundantly in corn oil, soybean oil, margarine, wheat germ oil, sunflower,safflower oils, etc. plays an important role in neurological functions and inhibition of platelet aggregation, regulation of enzymatic activity, free radical scavenger, etc..
The study in comparison of the effects of vitamin E analogues (d-alpha-, dl-alpha-, d-beta-, d-gamma-, and d-delta-tocopherols, d-alpha- and dl-alpha-tocopheryl acetates) and 2,2,5,7,8-pentamethyl-6-hydroxychroman (PMC) on melanogenesis in mouse B16 melanoma cells, showed a positive effects of d-beta-tocopherol and d-gamma-tocopherol, 2 variants of vitamin E, in skin whitening with lower skin toxicity, as well as improved skin pigmentation such as skin spots and freckles caused by UV exposure(27). According to Kobe University School of Medicine, alpha-Tocopheryl ferulate (alpha-TF), a compound containing alpha-T (a variant of vitamin E) and ferulic acid exhibited an efficient whitening effects, through suppressed melanogenesis and inhibited biological reactions induced by reactive oxygen species(28)(29).
Chinese Secrets to Fatty Liver and Obesity Reversal
A
Ovarian Cysts And PCOS Elimination
Back to Tofu and 600+ healthy recipe http://thetruestoriesstories.blogspot.ca/p/soy-recipes.html
Back to my Home page at http://thetruestoriesstories.blogspot.ca/
References
(a) Tyrosinase modulation by five Rwandese herbal medicines traditionally used for skin treatment by Kamagaju L1, Morandini R, Bizuru E, Nyetera P, Nduwayezu JB, Stévigny C, Ghanem G, Duez P.(PubMed)
(b) An ethnobotanical survey of medicinal plants used in Rwanda for voluntary depigmentation by Kamagaju L1, Bizuru E, Minani V, Morandini R, Stévigny C, Ghanem G, Duez P.(PubMed)
(c) Tyrosinase inhibition by extracts and constituents of Sideroxylon inerme L. stem bark, used in South Africa for skin lightening by Momtaz S1, Mapunya BM, Houghton PJ, Edgerly C, Hussein A, Naidoo S, Lall N.(PubMed))
(27) Comparison of the inhibitory effects of vitamin E analogues on melanogenesis in mouse B16 melanoma cells by Kamei Y1, Otsuka Y, Abe K.(PubMed)
(28) The depigmenting effect of alpha-tocopheryl ferulate on human melanoma cells by Funasaka Y1, Chakraborty AK, Komoto M, Ohashi A, Ichihashi M.(PubMed)
(29) Depigmenting effect of alpha-tocopheryl ferulate on normal human melanocytes by Funasaka Y1, Komoto M, Ichihashi M.(PubMed)
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