Posted by Chantel Martiromo
Skin aging is one of most visible ageing process which occurs constantly
in our skin organ. According to the Clinical Centre of Nis, certain
plant extracts may have the ability to scavenge free radicals, to
protect the skin matrix through the inhibition of enzymatic degradation,
or to promote collagen synthesis in the skin, affect skin elasticity
and tightness(a). Other suggested that free radicals induced domino
effects in production of reactive oxygen species, can react with DNA,
proteins, and fatty acids, causing oxidative damage and impairment of
antioxidant system, leading injuries damage regulation pathways of
skin, including wrinkles, roughness, appearance of fine lines, lack of
elasticity, and de- or hyperpigmentation marks(b).
The degradation of the epidermal and dermal layers of the extracellular
matrix (ECM), the non-cellular component present within all tissues and
organs, such as UV Exposure, decline of lysosomal/endosomal cathepsin K,
S and V activity(c) as well as environment factors such as irregular
dryness, dark/light pigmentation, sallowness, severe atrophy,
telangiectases, premalignant lesions, laxity, leathery appearance and
deep wrinkling, etc., cause modification of the surface of skin
and the physical properties of that lead to skin aging. Certain foods
have been found to be effective in protect the skin against natural
aging, including green tea and garlic.
Passionflower is also known as passion vines,, in the genus Passiflora , belonging to the family Passifloraceae,
native to southeastern parts of the America. The herb has been used in
traditional medicine in treating nervous tension including anxiety,
insomnia, seizures, sleep problems and hysteria.
Passion fruit seed extract, piceatannol,
and scirpusin B effected the keratinocyte by upregulated the glutathione
(GSH) levels in keratinocytes in a dose-dependent manner, and suppressed
the UVB-induced generation of reactive oxygen species (ROS), and
enhanced matrix-metalloproteinase (MMP)-1 activity(10). A flavone
chrysin from Passiflora caerulea Linn. and a benzoflavone moiety (BZF) recently isolated from Passiflora
incarnata Linn in rat skin study, showed a great potential for clinical
and therapeutic applications against the physiological and biochemical
effects of aging(11).
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References
(a) Skin ageing: natural weapons and strategies by Binic I1, Lazarevic V, Ljubenovic M, Mojsa J, Sokolovic D.(PubMed)
(b) Phytoconstituents as photoprotective novel cosmetic formulations by Saraf S1, Kaur CD.(PubMed)
(c) Differential expression of cathepsins K, S and V between young and aged Caucasian women skin epidermis by Sage J1, De Quéral D2, Leblanc-Noblesse E2, Kurfurst R2, Schnebert S2, Perrier E2, Nizard C2, Lalmanach G3, Lecaille F4.(PubMed)
(10) The protective effects of piceatannol from passion fruit (Passiflora edulis) seeds in UVB-irradiated keratinocytes by Maruki-Uchida H1, Kurita I, Sugiyama K, Sai M, Maeda K, Ito T.(PubMed)
(11) Beneficial effects of chrysin and benzoflavone on virility in 2-year-old male rats by Dhawan K1, Kumar S, Sharma A.(PubMed)
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