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Tuesday, January 13, 2015

Overcome Female Infertility: Human menopause gonadotrophins (HMG)

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Posted by Chantel Martiromo
Fertility is a natural process to insure the survival of human species. Through natural selection, we produce many offspring when the reproductive system works at it's peak in the suitable environment with plenty of food around. On the other hand, the reproductive system may completely shut down or work at it's minimum state in reproduction of offspring, when the environment is hostile including less foods around, war, epidemic, but regardless of all these factors, most women are capable of conceiving during their menstrual stages before menopause.

Human menopausal gonadotropins (HMG) contain both (LH) luteinizing hormone(LH) and follicle stimulating hormone(FSH) which are used for women with ovulation disorder by triggering the ovulation in production of follicle and egg. HMG is one of the fertility medical treatment which may be necessary for women, if artificial insemination is required such as IUI, IVF and other ART.

1. The HMG effects
By using the HMG to increase the levels of LH and FSH as resulting of inability of pituitary gland in LH, and FSH production, it helps to stimulate ovulation as we mentioned in previous article.
a) Ovulatory disorders
Ovulatory disorder ussually caused by low levels of LH and FSH as resulting in either of low levels of estrogen or damage of hypothalamus in releasing of GrNH, HMG increases the levels of LH and FSH directly without the need of hypothalamus secretion.

b) Pituitary gland abnormality
For what ever reason, some women's pituitary gland is not responsed to the secreting of the GrNH in production of LH and FSH or low levels of LH and FSH as resulting of pituitary gland malfunction. HMG increases levels of FH and FSH naturally, leading to ovulation.

c) Eggs production
HMG besides enhancing ovulation, it also acts directly to the ovarian in follicle and mature eggs production.

2. Side effects
a) Hyperovarian stimulation as resulting of over production of follicles inside of the ovaries.
b) Nervous disorder as resulting of interfering of hormone production. Symptoms include mood swing and depression.

3. Risk
Increasing the risk of multiple pregnancy by 40% of all pregnancies.

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