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Thursday, January 15, 2015

Overcome Female Infertility: Gonadotrophin-releasing hormone (GnRH)

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Gonadotrophin-releasing hormone (GnRH) is a synthesis GnRH hormone which helps to replace or increase the levels of GnRH in stimulating the production of LH and FSH by the pituitary gland

I. The effects of  Gonadotrophin-releasing hormone
GnRH may be used for infertile women, after HCG and ovulation dysfunction medication have been failed to stimulate the women reproductive ovulation. The process of LH and FSH production are controlled by the size and frequency of GnRH pulses.

1I. Ovulation
1. At the beginning, synthesis GnRH stimulates the low frequency GnRH pulses that cause the pituitary gland to release FSH that helps to stimulate ovulation and the production of follicle and egg.
2. Egg Extruding
As the follicle mature, synthesis GnRH helps to increase the production of estradiol that stimulates the high frequency GrRH pulses and stops the pituitary in secreting FSH and increases the production of LH leading to egg releasing into the Fallopian tube.

3. Side effects
a) Hot flashes.
b) Mood swings.
c) Vaginal dryness.
d) Decreased sexual interest.
e) Insomnia.
f) Headaches.

4. Risk
a) Bone loss
b) Heart disease
Raising the level of LDL cholesterol and decreasing your HDL cholesterol.


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