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Wednesday, August 7, 2019

Navy Bean, the Potential Treatment of Hypertension


High blood pressure or hypertension is a medical condition characterized by abnormally high blood pressure in the arteries. High blood pressure is also a condition in the cluster of metabolic syndrome that increases the risk of heart disease, stroke, and diabetes.

Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood.

Although at the early stage, high blood pressure usually does not cause symptoms, some patients in extreme cases may experience dizziness and light head, shortness of breath, nosebleeds, flushing, chest pain and visual changes.

Underlying medical conditions such as kidney disease and long term stress are associated with high blood pressure.

More precisely, according to the American hypertension Association, long-term untreated high blood pressure can induce complications such as
* Heart attack is casued by damages arteries due to high blood pressure that leads to the blockage or limited blood flow to the heart muscle.


* Stroke, damage blood vessels in the brain may be clogged and burst.


* Heart failure, high blood pressure increases the risk of enlarged-heart that limits the heart function in blood circulation

Conventional hypertensive medications have undoubtedly prevented many deaths from heart disease in the past 30 years, but they have many side effects.

If you current taking hypertensive medicine, please make sure you know all the side effects for the preventive measure.

Some researchers also found that excessive energy intake and obesity are major causes of hypertension.

Dr. Savica V, the lead author in the study "The effect of nutrition on blood pressure" wrote, "Obesity is associated with increased activity of the renin-angiotensin-aldosterone and sympathetic nervous systems, possibly other mineralocorticoid activity, insulin resistance, salt-sensitive hypertension, and excess salt intake, and reduced kidney function".

High sodium chloride intake strongly predisposes to hypertension".

"Increased alcohol consumption may acutely elevate blood pressure. High intakes of potassium, polyunsaturated fatty acids, and protein, along with exercise and possibly vitamin D, may reduce blood pressure".


The small, white navy bean, also called pea bean or haricot, popular in both dry and green forms, is very popular in Britain and the US, native to Peru. It is now grown and consumed across the world, due to their numerous health benefits.

With an aim to find a potential ingredient for the treatment of hypertension, researchers investigated the inhibitory activities of the navy bean by preparation of navy bean milk (NBM) subjected to fermentation of four lactic acid bacteria (LAB) strains, namely, Lactobacillus helveticus MB2-1, Lactobacillus plantarum B1-6, and Lactobacillus plantarum 70810.

According to the tested assays, all fermented NBM showed higher angiotensin I-converting enzyme (ACE) inhibitory activity compared to the unfermented ones.

By comparison of each strain, researchers found that 2 h, 3 h, and 5 h are the optimum fermentation periods for respectively L. plantarum 70810, L. plantarum B1-6 and L. bulgaricus.

Compared to the IC value without causing an intestinal disturbance, the extracts fermented by L. plantarum B1-6 exerted the lowest IC50 value of 21 ± 2.1 μg protein ml(-1).

Angiotensin-converting enzyme (ACE) is a central component of the renin-angiotensin system (RAS), which controls blood pressure by regulating the volume of fluids in the body.


In other words, the effect of LAB fermentation on the degradation of navy lean proteins and the capacity to release ACE inhibitory peptides may have a strong effect in the inhibition of hypertension.

Dr. Rui X, after taking other factors into account wrote, "The approach was promising to obtain probiotic products with the potential to serve as functional ingredients targeting hypertension".


Taken altogether, the fermented navy bean may be considered a remedy for the prevention and treatment of hypertension, pending to the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Enrichment of ACE inhibitory peptides in navy bean (Phaseolus vulgaris) using lactic acid bacteria by Rui X1, Wen D, Li W, Chen X, Jiang M, Dong M. (PubMed)
(2) The effect of nutrition on blood pressure by Savica V1, Bellinghieri G, Kopple JD(PubMed)

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