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Monday, January 13, 2014

Serum Potassium and nonalcoholic fatty liver disease

Posted by Chantel Martiromo,  Article By Kyle J. Norton  

Dietary Minerals are the group of minerals essential for our body to sustain normal functions and physical health.
In General, potassium is a very essential mineral to the human body for maintaining to build proteins and muscle, break down carbohydrates, maintain normal body growth and normal heart electricity, etc.
Fatty liver disease.
Fatty liver disease is defined as a condition of accumulation of fat in the liver, including people who drink little or no alcohol (Non alcohol fatty disease) or who are excessive alcohol drinking (Alcohol fatty liver disease). The disease can even occur after a short period of heavy drinking (acute alcoholic liver disease). More than 15 million people in the U.S. either abuse or overuse alcohol with fatty liver diseases with fat makes up 5-10 percent of liver weight.
Non-alcoholic fatty liver disease (NAFLD) encompasses a wide spectrum of clinical conditions, actually representing an emerging disease of great clinical interest(4).

The benefits
Nonalcoholic fatty liver disease (NAFLD) are associated to increased risk of metabolic syndrome. In the study of in 8592 subjects with NAFLD (30·3%) and gradually decreased across serum potassium quartiles, to investigate the association of serum potassium with the risk of prevalent NAFLD. The result showed a significant relation between serum potassium level and NAFLD in women, younger subjects, those with insulin resistance and central obesity. Other in the study to investigate the association between NAFLD and primary aldosteronism (PA), and to identify determinants of NAFLD in this condition, showed that Serum potassium was lower in primary aldosteronism (PA) than in LREH patients with NAFLD (P < 0.001), while it was similar in PA and LREH patients without NAFLD.

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(1) Low serum potassium level is associated with nonalcoholic fatty liver disease and its related metabolic disorders by Sun K, Lu J, Jiang Y, Xu M, Xu Y, Zhang J, Xu B, Sun J, Sun W, Ren C, Liu J, Wang W, Bi Y, Ning G.(PubMed)
(2) Nonalcoholic fatty liver disease in primary aldosteronism: a pilot study by Fallo F, Dalla Pozza A, Tecchio M, Tona F, Sonino N, Ermani M, Catena C, Bertello C, Mulatero P, Sabato N, Fabris B, Sechi LA.(PubMed)
(3) Review article: the diagnosis of non-alcoholic fatty liver disease -- availability and accuracy of non-invasive methods by Festi D, Schiumerini R, Marzi L, Di Biase AR, Mandolesi D, Montrone L, Scaioli E, Bonato G, Marchesini-Reggiani G, Colecchia A.(PubMed)

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