Posted by Chantel Martiromo
Alzheimer's disease is a brain
disorder correlated with major
reductions of neurons to the respective target areas
and named after German physician Alois Alzheimer. Alzheimer's
destroys brain cells, causing cognitive modalities severe enough to affect language communication, memory,
lifelong hobbies or social life. Alzheimer's gets worse over time, and
it is fatal.
According to statistic, over 25 million people in the world today are affected by dementia and most are suffering from Alzheimer's disease. It may be results of cigarette smoking, midlife high blood pressure and obesity, diabetes,
and cerebrovascular lesions) and the possible beneficial roles of
psychosocial factors (eg, high education, active social engagement,
physical exercise, and mentally stimulating activity)(1)
Strong evidences emerged in epidemiological studies suggested that
certain herbs(2) may have potential in reduced risk and treatments of
Alzheimer's disease but geographic source of the plant material,
climatation,
and time of harvest may effect their effectiveness. It is understandable
that commercially available herbal medicinal products with the same
herbal
ingredients vary in their content and concentration of chemical
constituents when compared between manufacturers.
Papaver somniferum is a genus of Papaver, belonging to the family Papaveraceae, native to the Mediterranean Basin, Southeastern Europe, and Western Asia. The herb has been used in folk medicine for treating asthma, stomach illnesses, and bad eyesight.
Opium poppy exerted it neuroprotective effect through interaction of
alkaloid opioids of herb with endogenous opiate receptors in the brain,
according to Medical Research Council, Newcastle General Hospital(29).
Some alkaloids isolated from plants, or are derived from templates of
compounds from plant sources have been in clinical use for treatment of
cognitive disorders(30).
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References
(1) Epidemiology of Alzheimer's disease: occurrence, determinants, and strategies toward intervention. by Qiu C, Kivipelto M, von Strauss E.(PubMed)
(2) The Use of Herbal Medicine in Alzheimer's Disease—A Systematic Review by Leopoldo Luiz dos Santos-Neto,1 Maria Alice de Vilhena Toledo,2 Patrícia Medeiros-Souza,3 and Gustavo Almeida de Souza(PubMed)
(29) Medicinal plants and Alzheimer's disease: from ethnobotany to phytotherapy by Perry EK, Pickering AT, Wang WW, Houghton PJ, Perry NS.(PubMed)
(30) Plants with traditional uses and activities, relevant to the management of Alzheimer's disease and other cognitive disorders by Howes MJ, Perry NS, Houghton PJ(PubMed)
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