Infectious diseases are a medical condition caused by pathogenic microorganisms, including bacteria, viruses, parasites or fungi.
Most cases of infectious diseases are contagious by spreading directly or indirectly, from one person to another.
In other words, if you kiss, or are coughed or sneezed on by an infectious person, you are at risk of developing the same infectious disease.
According to the statistic provided by the World Health Organization, 3 infectious diseases were ranked in the top ten causes of death worldwide in 2016.
More precisely, lower respiratory infections, diarrheal diseases, and tuberculosis induced 3.0 million, 1.4 million, and 1.3 million deaths, respectively.
Conventionally, most cases of infectious diseases except those caused by viruses are treated by antibiotics.
If you are currently taking one of the antibiotics for the treatment of infectious diseases, please make sure you know all the side effects for preventive measure.
Diagnosis of the type of bacteria that causes the disease in most cases is important for precisive targeting.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Researchers on finding a natural compound as the antibiotic alternative for the treatment of infectious diseases with no side effects evaluated the antibacterial properties of Allium sativum (garlic) cloves and Zingiber officinale (ginger) rhizomes against multi-drug resistant clinical pathogens causing nosocomial infection.
The study included two crude garlic cloves and ginger rhizomes with 95% (v/v) ethanol tested against five gram-negative and two-gram positive multi-drug resistant bacterial isolates.
Application of the extracts showed significant inhibition against all tested isolates.
The highest inhibition zone of garlic (19.45 mm) was found in the Pseudomonas aeruginosa (P. aeruginosa), with the minimal inhibitory concentration as low as 67.00 µg/mL.
Based on the findings, researchers wrote in the final report, "Natural spices of garlic and ginger possess effective anti-bacterial activity against multi-drug clinical pathogens and can be used for prevention of drug-resistant microbial diseases and further evaluation is necessary".
Additionally, in order to know more information about the ginger antibacterial property, researchers also examined the antimicrobial potency of fresh, natural and commercial dried Allium sativum and Zingiber officinale extracts against seven local clinical bacterial isolates such as Escherichia coli.
Compared to garlic extract, chloroform and diethyl ether extracts of Z. officinale showed a greater zone of inhibition of tested pathogens except for P. aeruginosa and E. coli.
Furthermore, all extracts of A. sativum and Z. officinale have a strong antibacterial effect compared to recommended standard antibiotics through activity index.
The efficacy of ginger against bacterial infectious diseases was attributed to the presence of various phytochemicals such as tannins, phenols, alkaloids, steroids, and saponins.
Dr. the lead scientist said, "These findings provide new insights to use A. sativum and Z. officinale as potential plant sources for controlling pathogenic bacteria and potentially considered as cost-effective in the management of diseases and to the threat of drug resistance phenomenon".
Take all together, ginger processed a high amount of bioactive compounds may be considered an antibiotic alternative for prevention and treatment of bacterial infectious diseases, pending to the confirmation of large sample size and multicenter human study.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
(1) Biological activities of Allium sativum and Zingiber officinale extracts on clinically important bacterial pathogens, their phytochemical and FT-IR spectroscopic analysis by Awan UA1, Ali S1, Shahnawaz AM1, Shafique I1, Zafar A1, Khan MAR2, Ghous T3, Saleem A4, Andleeb S. (PubMed)
(2) Antibacterial effect of Allium sativum cloves and Zingiber officinale rhizomes against multiple-drug resistant clinical pathogens by Karuppiah P1, Rajaram S. (PubMed)
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