In a study of isoflavones and plant extracts were tested for their effect on cell proliferation, apoptosis induction and cell cycle arrest. Isoflavones and plant extracts were applied in proliferation assays on 11 human cancer cell lines (representing cancers of the colon, prostate, breast, cervix, liver, pancreas, stomach and ovaries) and a fibroblast line to detect cytotoxic activity, conducted by University of Natural Resources and Life Sciences Vienna, posted in
US National Library of Medicine National Institutes of Health, researchers filed the conclusion that Isoflavones and plant extracts from soy and red clover, respectively, do not promote the growth of human cancer cells but induce decreased cell proliferation, increased apoptosis and cell cycle arrest. These results indicate that isoflavones can be considered safe compounds.
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