Cruciferous vegetables are the group of vegetables belonging to the family Brassicaceae, including cauliflower, cabbage, cress, bok choy, broccoli, etc.
Intake of cruciferous vegetables regularly may reduce risk and improve the treatment of multiple chronic diseases.
Chronic diseases are medical conditions, lasting more than three months.
A recent study conducted by the joint study lead by the Suzhou Science and Technology Town Hospital suggested that sulforaphane (SFN), a derivative of glucoraphanin presented in cruciferous vegetables, exhibited strongly therapeutic effects on inflammation-related diseases in the induction of chronic pain in animals with chronic constriction injury.
Dr. Wang C and Dr. Wang C, suggested that Sulforaphane (SFN) reduced inflammation-induced pain may be a result of its attenuation of behavioral hypersensitivity without affecting SFN modulation of inflammatory cytokines.
Addition to that, fhe chemical compound also found to enhance the production of Nrf2, a master regulator of detoxification and also antioxidant, anti-inflammatory and other cytoprotective mechanisms, in prevented and/or treated a large number of chronic inflammatory diseases, including various cardiovascular diseases, kidney diseases, lung diseases, diseases of toxic liver damage.
Dr. Houghton CA, the lead author of the study said, " By virtue of its lipophilic nature and low molecular weight, sulforaphane displays significantly higher bioavailability than the polyphenol-based dietary supplements that also activate Nrf2. Nrf2 activation induces cytoprotective genes such as those playing key roles in cellular defense mechanisms including redox status and detoxification"
Indole-3-carbinol (I3C), other common phytochemical found in cruciferous vegetables, maybe another potential agent in the prevention of chronic diseases, through its effect in biological activities on cellular and molecular levels, according to a joint study lead by the Poznan University of Medical Sciences.
Taking together, there is no doubt that intake of cruciferous Vegetables regularly has a potential property in reduced risk and treatment of multiple chronic illnesses, because of its effects in improved functions of over 500 genes in cellular defense mechanisms including redox status and detoxification and anti-inflammatory in the induction of chronic diseases.
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Sourcesd
(1) Anti-nociceptive and anti-inflammatory actions of sulforaphane in chronic constriction injury-induced neuropathic pain mice by Wang C1, Wang C2.(PubMed)
(2) Indole-3-Carbinol and Its Role in Chronic Diseases by Licznerska B1, Baer-Dubowska W2.(PubMed)
(3) Nrf2, a master regulator of detoxification and also antioxidant, anti-inflammatory and other cytoprotective mechanisms, is raised by health promoting factors by Pall ML1, Levine S2.(PubMed)
(4) Sulforaphane and Other Nutrigenomic Nrf2 Activators: Can the Clinician's Expectation Be Matched by the Reality? by Christine A. Houghton, Robert G. Fassett, and Jeff S. Coombes(PubMed)
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