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Monday, November 11, 2019

Kidney Beans, the Potential anti-human immunodeficiency virus (anti-HIV) Natural Whole Food

Kidney bean may process potential beneficial health effects in anti-human immunodeficiency virus (anti-HIV), the recent joint study suggested.
Kidney bean is popular food, with kidney shape, strong flavor and color in reddish-brown in nature, used often as an excellent dietary selection because of enormous health benefits with a good source of protein and minerals.

Human immunodeficiency virus(HIV) is the viral cause of acquired immunodeficiency syndrome overtime if infected

According to the Chinese University of Hong Kong, Lectins, class of sugar-binding proteins found abundantly in all beans, including kidney bean exhibited antiviral effect against the HIV-1-RT activity.

Dr. Ng TB, the lead author in the study of inhibitory effects of antifungal proteins on human immunodeficiency virus type 1 said, "(Kidney beanexert the) ability to inhibit human immunodeficiency virus type I (HIV-1) reverse transcriptase(, an enzyme regulated the formation of RNA from a DNA), protease(an enzyme that breaks down proteins and peptides) and integrase (produced by HIV virus), enzymes essential to the life cycle of HIV-1".

The study also indicated that the efficacy of all leguminous antifungal proteins with potential in inhibited HIV-1 to some extent is attributed to activities of reverse enzymes function.

Some researchers insisted that Kidney beans also exerted immunomodulatory activity in regulated presences of B and T cell immune response directed against the glycine-rich cell wall protein (GRP) in patients with different autoimmune disorders, including immune dysfunction in patients with human immunodeficiency virus (HIV) infection.

Taking all together, Kidney bean may process anti-viral property against human immunodeficiency virus causing acquired immunodeficiency syndrome through the expression of reserve function of certain enzyme and induced immunomodulatory exhibition in regulated B and T cell in an autoimmune response.


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Sources
(1) Phaseolus vulgaris Lectins: A Systematic Review of Characteristics and Health Implications by He S1,2,3, Simpson BK3, Sun H1, Ngadi MO4, Ma Y2, Huang T5.(PubMed)
(2) A lectin with anti-HIV-1 reverse transcriptase, antitumor, and nitric oxide inducing activities from seeds of Phaseolus vulgaris cv. extralong autumn purple bean by Fang EF1, Lin P, Wong JH, Tsao SW, Ng TB.(PubMed)
(3) Inhibitory effects of antifungal proteins on human immunodeficiency virus type 1 reverse transcriptase, protease and integrase by Ng TB1, Au TK, Lam TL, Ye XY, Wan DC.(PubMed)
(4) A hemagglutinin from northeast red beans with immunomodulatory activity and anti-proliferative and apoptosis-inducing activities toward tumor cells by Chan YS1, Wong JH, Fang EF, Pan W, Ng TB.(PubMed)
(5) Glycine-rich cell wall proteins act as specific antigen targets in autoimmune and food allergic disorders by Lunardi C1, Nanni L, Tiso M, Mingari MC, Bason C, Oliveri M, Keller B, Millo R, De Sandre G, Corrocher R, Puccetti A.(PubMed)
(6) HIV and autoimmunity by Zandman-Goddard G1, Shoenfeld Y.(PubMed)

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