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Wednesday, November 20, 2019

Black Bean, The Best Functional Food for Hypertension

Adding a portion of cooked black beans in your diet may substantially. reduce risk and enhanced treatment of hypertension, a respectable university study suggested.

Hypertension is a medical syndrome characterized by abnormally high blood pressure, affecting high portions of the population in the world, according to the statistic.



Black bean, a small roughly ovoid legume with glossy black shells, genus Phaseolus, belongings to the family Fabaceae can be bought in most grocery stores all around the year in dried and canned forms. It is believed that black bean was first domesticated growth in South America.

According to the joint study led by the University of Illinois at Urbana-Champaign, Mexican black bean isolated proteins peptidase-IV (DPP-IV), after pepsin/pancreatin digestion, showed a significant effect in reduced hypertension at dose with IC50 = 0.03-0.87 mg and dry weight and inhibited α-glucosidase, a protein related to early onset of diabetes, ranged from 36.3 to 50.1% mg-1 DW.


The efficacy of the anti-hypertension of the black bean is attributed to the elevation of antioxidant capacity fighting against the forming of reactive oxygen species (ROS), Dr. Mojica L, the lead author insisted.



In an article published at the Research Journal of Pharmaceutical, Biological and Chemical Sciences,
black bean crude extract decreased both systolic as well as diastolic BP in a dose-dependent manner (1-100 mg/kg).

The article also indicated that the fall of both pressures may be due to the presence of phytochemicals saponin fraction and mediagenic acid glucoside in the crude extract.


Furthermore, azuki bean (Vigna angularis) seed coats (ABSC) with different color, containing high amount of polyphenols attenuated vascular oxidative stress and inflammation associated with hypertension in the experiment of hypertensive rats (SHR) and control normotensive Wistar-Kyoto (WKY) rats.

More importantly, treated mice with azuki bean (Vigna angularis) seed coats (ABSC), suppressed the elevation of SBP throughout the treatment period of 8 weeks, by decreasing of NADPH oxidase inactivated free radical expression and increasing antibody p47phox and Nox4 against radical formation through mRNA expression.

Dr. Mukai Y, the lead researcher said, " polyphenol-containing ABSC could attenuate vascular oxidative stress and inflammation during the progression of hypertension, and this may lead to an improvement in hypertension".

The findings suggested that black bean with various chemical constituents may be considered as a functional and integrated food for reduced hypertensive risk and treatment of high blood pressure.


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Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Characterization of peptides from common bean protein isolates and their potential to inhibit markers of type-2 diabetes, hypertension and oxidative stress by Mojica L1,2, Luna-Vital DA1,3, González de Mejía E1.(PubMed)
(2) Comparative Review on Harmless Herbs with Allopathic Remedies As AntiHypertensive by Joshi UH*, Ganatra TH, Bhalodiya PN, Desai TR, Tirgar PR(Research Journal of Pharmaceutical, Biological and Chemical Sciences)
(3) Polyphenol-containing azuki bean (Vigna angularis) seed coats attenuate vascular oxidative stress and inflammation in spontaneously hypertensive rats by Mukai Y1, Sato S.(PubMed)

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