Cranberry Juice improves Quality of Life in Patients with Rheumatoid Arthritis

Rheumatoid Arthritis is a chronic disorder characterized by inflammation of the flexible (synovial) joints and tissues and organs in the body.

The disease affects more women than men and generally occurs after the ages of 40, causing the diminished quality of life of many elders.

According to the statistics provided by the CDC, musculoskeletal disorders (MSDs) affect over 52 millions of adults in the US alone, including 294,000 children under age 18 with some form of arthritis or rheumatic conditions.

Rheumatoid arthritis was found to induce bone loss through elevating bone resorption without increasing bone formation.

Patients with rheumatoid arthritis (RA) often associate to valgus deformities of the feet and deformities of gait due to body function due to an effort to support the collapsing longitudinal arch of the foot.

Long-term bone damage and the prolonged onset of the disease can induce deformities of hand and wrist and small peripheral joints (such as fingers and wrist) due to chronic inflammation.

The effects of muscle strength in patients with RA may contribute to the prevalence of functional limitations physically that can affect daily living and quality of life.

Furthermore, rheumatoid nodules, lump on the skin, closed to the joint have been found to affect the joints of patients with RA.

Moreover, morning stiffness, a marker of inflammatory activity that reflects functional disability and pain is a very common symptom of patients in the early stage of rheumatoid arthritis.


On finding a potential compound for the treatment of inflammatory disease, researchers examined the effect of cranberry juice consumption on several inflammatory biomarkers and on the disease activity of patients with RA.

The prospective study included 41 women diagnosed with RA.randomly divided to control group (n = 18) maintained their usual diet and the cranberry group (n = 23) received 500 mL/d of low-calorie cranberry juice.

Compared to baseline values, the cranberry group showed a decrease in the values of Disease Activity Score 28 (DAS28) (P = 0.048) and anti-cyclic citrullinated peptide (anti-CCP), the antibody present in most rheumatoid arthritis patients (P = 0.034) after 90 d of treatment without affecting the inflammatory biomarkers.

The results strongly suggested that cranberry juice improves the rheumatoid arthritis symptoms and decrease the disease activity that benefits RA patients.

Taken altogether, cranberry may be considered a remedy for the improvement of rheumatoid arthritis, pending to the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Cranberry juice decreases disease activity in women with rheumatoid arthritis by Thimóteo NSB1, Iryioda TMV1, Alfieri DF1, Rego BEF1, Scavuzzi BM1, Fatel E2, Lozovoy MAB3, Simão ANC3, Dichi I. (PubMed)