Kidney bean, The Natural Whole Food with Anti-Microbial Activities

Recently study conducted by renowned institutes suggested that oral administrated kidney bean may have potential health benefits in reduced risk and treatment of microbial infection.

Kidney bean is popular because of its kidney shape, strong flavor and color of reddish-brown in nature, It is often an excellent dietary selection with no cholesterol and good sources of protein and mineral.



According to the research article posted at the Journal of Microbial & Biochemical Technology, lectins isolated from kidney bean seed displayed a significant antifungal and anti-bacteria activity on many straits of Staphylococcus aureus ATCC 6538, and Streptococcus mutants ATCC 25175, Pseudomonas aeruginosa ATCC 10145 and Klebsiella pneumonia and Candida Albicans.




The chemical compound lectins also manifested inhibitory effects on human immunodeficiency virus-1 reverse transcriptase of enzymes in catalyzed the formation of RNA from a DNA and alpha-glucosidase in lower the rate of glucose absorption.

Dr. Ye XY, the lead author in the study said, " It(Lectins) exerted a suppressive effect on the growth of the fungal species Fusarium oxysporum, Coprinus comatus, and Rhizoctonia solani".

Other researchers suggested that the potency of kidney bean in exhibited antimicrobial effect may be a result of its source of nondigestible fermentable components and phenolic compounds.

In healthy mice exposed to dextran sodium sulphate (DSS) (via drinking water, 2% DSS w/v, 7 days) induced colitis and fed with one of three isocaloric diets: basal diet control (BD), or BD supplemented with 20% cooked white (WK) or dark red kidney (DK) bean flour for 3 weeks, mice fed with both bean diets reduced, significantly disease severity, colonic damage and exerted increased mRNA expression of antimicrobial effects involved innate immunity and protected mucosa from insults through stabilizing the mucus layer and promoted healing of the epithelium and reduced pro-inflammatory cytokines demonstration.

Furthermore, cooked white (WK) or dark red kidney (DK) bean fed mice also enhanced microbial-derived SCFA metabolite production in regulated fermentation products, gut barrier integrity, and the microbial defensive response .....

Taking together, Kidney beans ( Phaseolus) showed to process a strong anti-microbial effect in reduced infection and inflammation caused by straits of bacteria and fungi, especially in protecting the digestive system against inflammation cause of colitis.


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Sources
(1) Antimicrobial Activities of Lectins Extracted from Some Cultivars of Phaseolus vulgaris by SeedsEinas Hamed El-S1, Magda Mahmoud Ibrahim El-A2and Mervat Mounir S1(Journal of Microbial & Biochemical Technology)
(2) White and dark kidney beans reduce colonic mucosal damage and inflammation in response to dextran sodium sulfate by Monk JM1, Zhang CP1, Wu W2, Zarepoor L1, Lu JT1, Liu R2, Pauls KP3, Wood GA4, Tsao R2, Robinson LE5, Power KA6.(PubMed)
(3) Isolation of a homodimeric lectin with antifungal and antiviral activities from red kidney bean (Phaseolus vulgaris) seeds by Ye XY1, Ng TB, Tsang PW, Wang J.(PubMed)