Black Bean, A Potent Anti Diabetes whole Food Medicine

Black bean with abundant phytochemicals and fibers may be considered as a functional food in reduced risk and treatment of diabetes, a renowned university postulated.

Black bean, small roughly ovoid legumes with glossy black shells, genus Phaseolus, belongings to the family Fabaceae can be bought in most grocery stores all around the year in dried and canned forms. It is believed that black bean was first domesticated growth in South America.

Diabetes is a medical condition characterized by insufficient insulin entering the bloodstream to regulate the glucose. It is either caused by cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol. In some cases, diabetes is also caused by allergic reactions of cells in the immune system.



According to the University of Illinois at Urbana-Champaign, bioactive peptides protein isolated from black bean (Phaseolus vulgaris L.) exhibited anti-diabetic activity by inhibiting important molecular markers, a particular sequence of DNA related to diabetes.

The study also stressed that certain types of peptides showed some degrees of different inhibitory potential on α-glucosidase, compared to others.

Mice fed with dietary supplementation of black bean extracts also significantly enhanced hyperglycemia and homeostasis measured by insulin resistance index, observed by expression of glucose intolerance, and regulated insulin secretion.


More importantly, in the comparison of protective effects of black bean peel extract (BBPE), pomegranate peel extract (PPE) and a combination of the two (PPE + BBPE) on streptozotocin-induced DM mice, mice treated with black bean or combination of black bean showed a strong improvement of fasting blood glucose and insulin levels, and pancreas weight index exerted through antioxidant in reduced oxidative expression.

Mice treated with PPE + BBPE also indicated a positive influence in ameliorated oxidative stress-against damage of pancreatic islets.

The finding evidence suggested that black bean, as a functional food may have a potential and therapeutic effect in the prevention and treatment of diabetes.



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Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Sources
(1) Optimization of enzymatic production of anti-diabetic peptides from black bean (Phaseolus vulgaris L.) proteins, their characterization and biological potential by Mojica L1, de Mejía EG1.(PubMed)
(2) Black Adzuki Bean (Vigna angularis) Extract Protects Pancreatic β Cells and Improves Glucose Tolerance in C57BL/6J Mice Fed a High-Fat Diet by Kim M1, Kim DK2, Cha YS1.(PubMed)
(3) Extracts of black bean peel and pomegranate peel ameliorate oxidative stress-induced hyperglycemia in mice by Wang JY1, Zhu C1, Qian TW1, Guo H1, Wang DD1, Zhang F1, Yin X1.(PubMed)