Dried Peas (Legumes) in Reduced Risk and Treatment of Prostate Cancer

Intake of legume, particular dried Peas daily and regularly may reduce the risk and treatment of prostate cancer, some scientists suggested.

Dried pea is a small but nutritionally mighty member of the legume family, genus Pisum belongings to the family Fabaceae with healthy source of proteins, fibers, vitamins, and minerals.

Prostate cancer is a medical condition characterized by irregular cell growth in the prostate. Over 11.4 million men will be diagnosed with prostate cancer at some points during their lifetime, according to statistics.

According to the study at the Yamagata University School of Medicine, in the investigated effect of some flavonoids, isolated from fruits, vegetables, and peas in the risk of prostate cancer, using human LNCaP prostate cancer cells researchers found that
1. Genistein, a member of the group of flavonoids exerted a significant effect in cell cycle arrest at the G2/M phases, attributed to the suppression of cyclin B expression.

2. The suppression of genistein induced the cyclin-dependent kinase inhibitor p21 which plays an important role in cell cycle progression.



The effect of flavonoids to induce prostate cancer cell apoptosis was attributed to suppression of proteins in control of the division of cells by activating cyclin-dependent kinase (Cdk) enzymes in the production p21 antibody.



This result may provide additional persuasion for holistic practitioners to ask their prostate problematic clients to add a portion of rich flavonoid foods into their daily diet.

In concerns of the progressive effect of dietary and lifestyle characteristics and implication of risk of prostate cancer, researchers at the Loma Linda University School of Medicine conducted study men of completed a detailed lifestyle questionnaire in 1976 with monitored for cancer incidence until the end of 1982. During the 6-year follow-up period, researchers indicated that 180 histologically confirmed prostate cancers were detected among some 78,000 man-years of follow-up.


Further analysis of the returned questionnaire from the subjects, researchers filed the following interesting results
1. Contrast to general belief, age was inversely associated with risk of prostate cancers
2. History of prostate "trouble" was associated with a 60% increase in the risk of cancer development
3. Increased intake of animal product consumption was also associated with increased risk of the cancer

More intrusively, researchers also emphasized that increasing consumption of beans, lentils, and peas, ...........were all associated with significantly decreased prostate cancer risk.

The result of findings although suggested that legume may have a positive effect on reduced prostate cancer incidence, it doesn't mean that you can just eat a large portion of such foods every day and expected the problem will go away. Negative dietary and lifestyle habits sometimes have a strong implication of the outcome.



More importantly, in the study to confirm the effective of common constituents of seeds (rice, beans, and maize) in ameliorated risk of breast, colon, and skin cancers in animals, researchers suggested that antioxidant-rich in seeds may play an important role in reduced oxidative stress and ionizing radiation in initiated cancer and cancer progression.

Dr. Thapa D. in response to the effect of antioxidant and risk of prostate cancer, said, "It has also been established that inflammation is a precursor in neoplastic transformation of the prostate". and "Although a vast body of experimental and clinical evidence shows efficacy of antioxidants as preventive strategies for prostate cancer, there is a lack of consistent agreement in outcomes especially from recent large-scale randomized clinical trials".



The suggestion indicated that other components that have not been discovered may have a significant effect in reduced risk of prostate cancer besides legume antioxidant activities.

Most studies of legume in attenuated risk of treatment of prostate cancer is in the experiment state with small sample size and contradiction are expected due to many factors including studied designed, sample chosen, race, eating habits,......., therefore a large sample and cohost study, taking into account of other confounders are necessary to confirm this validation.

However, with the information findings, it is safe to suggest that adding some portions of legume, such as peas, into your diet may have a profound effect on the reduced risk of prostate cancer.



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Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Sources
(1) Effect of flavonoids on cell cycle progression in prostate cancer cells by Kobayashi T1, Nakata T, Kuzumaki T.(PubMed)
(2) Cohort study of diet, lifestyle, and prostate cancer in Adventist men by Mills PK1, Beeson WL, Phillips RL, Fraser GE.(PubMed)
(3) Protease inhibitors: possible anticarcinogens in edible seeds by Troll W, Wiesner R.(PubMed)
(4) Antioxidants for prostate cancer chemoprevention: challenges and opportunities by Thapa D1, Ghosh R.(PubMed)