Beet, Reduced Risk of Cardiovascular Disease by Balancing Endothelial Function

Beetroot with rich in inorganic nitrate may be used as dietary supplementation or functional food to improve endothelial function via reduced expression of harmful free radicals, a respectable institute study illustrated.

The endothelium is a thin membrane lined the inside of the heart and blood vessels with function in control vascular relaxation and contraction, as well as enzymes that control blood clotting, immune function and platelet adhesion.

Endothelial dysfunction, due to the inability of the arteries to dilate fully, may exhibit high blood pressure, diabetes, high cholesterol.... in promoting stroke and heart attacks.

Beet, best known as the beetroot or garden beet, belonging to the amaranth family, is a perennial plant with leafy stems growing to 1–2 m tall.


In a total of 20 healthy overweight and slightly obese men with a BMI between 28 and 35 kg/m(2) received in random order a mixed meal of 56.6 g of fat with beetroot juice or a control drink, oral administration of beetroot juice (140 mL) with approximately 500 mg dietary nitrate group, showed a significant improvement of postprandial endothelial function in compared control.

The efficacy of beet juice in attenuated postprandial impairment of flow-mediated dilation (FMD) following a mixed meal, probably due to the expression of increased plasma NO concentrations in the blood stream, according to the Maastricht University Medical Center.

Furthermore, beet roots with biological activity provided a natural source of nitric oxide (NO) in reduced risk of endothelium dysfunction inducing the imbalance between vasodilation and vasoconstriction of arterial vessels.

The study also suggested that phytochemical betalain isolated from beetroot may also hold a significant effect in maintain healthy endothelium function, acting simultaneously with increasing levels of nitric oxide (NO).

More importantly, the review database of literature fromMEDLINE, EMBASE and Scopus databases from inception until November 2014, 9 crossover trials and three parallel trials met inctlusion criteria, included a total of 246 participants with 10-64 participants per study, also indicated the efficacy of inorganic nitrate and beetroot consumption in reduced risk of cardiovascular disease by improved vascular function. But the effect on endothelial function was significantly associated with the dose depended of inorganic nitrate, found abundantly in the vegetable

The finding evidences indicated that beetroot may be considered as a promising therapeutic treatment in ameliorated risk of cardiovascular disease through improvement of vascular and endothelial functions.




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Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Sources
(1) Beetroot juice improves in overweight and slightly obese men postprandial endothelial function after consumption of a mixed meal by Joris PJ1, Mensink RP.(PubMed)
(2) The potential benefits of red beetroot supplementation in health and disease byClifford T1, H Watson G2,3, West DJ4, Stevenson EJ5.(PubMed)
(3) Effects of inorganic nitrate and beetroot supplementation on endothelial function: a systematic review and meta-analysis by Lara J1, Ashor AW2,3, Oggioni C2, Ahluwalia A4, Mathers JC2, Siervo M2. (PubMed)