Black Bean, A Potent Anti Breast Cancer Functional Food

Intake a portion of black bean regularly may reduce the risk of early-onset and treatment of breast cancer, a renowned institute study suggested.

Breast cancer (malignant breast neoplasm) is a condition of abnormal cell growth in the breast area.



Breast cancer in most cases starts in the tissues of the breast either from the inner lining of milk ducts (Ductal carcinoma) or the lobules (Lobular carcinoma) that supply the ducts with milk. but in a rare instances, breast cancer may arise from other areas of the breast.


Black bean, small roughly ovoid legumes with glossy black shells, genus Phaseolus, belongings to the family Fabaceae can buy in most grocery stores all around the year in dried and canned forms. It is believed that black bean was first domesticated growth in South America.

In the study of water-soluble condensed tannins isolated from black beans against Hs578T breast cancer cells, the preparation at 0.24-24 microM in dose-dependent induced cancer cell death by apoptosis but did not affect the growth of normal cells, as shown by observation assay.
The efficacy of water-soluble black bean condensed tannins at 24 microM in suppressed the breast cancer cells may be attributed to the phytochemicals in reduced coagulation of remained blood in stimulated cancer cell migration and regulated the growth of breast tumor in the formation of new blood vessels.


Furthermore, according to the National Taiwan University, fermentation products of soybean, black bean, and green bean mixture (BN999) showed a significant effect in inhibiting the growth of human breast cancer AU565 cells in increased expression of multiple apoptotic regulators in induced apoptosis.
The fermentation product also exerted an impressive activity in induced apoptosis in various human cancer cells but not in normal human cells, Dr, Chia JS, the lead author insisted.

More importantly, Dr. Dong M, the lead researcher at the Cornell University, in the finding of major phytochemicals of black bean which may have a powerful effect in treatment of breast cancer suggested, that out of newly found flavonoids, only 6 (5, 7, 8, 9, 11, 19, 20) of them showed potent antioxidant and antiproliferative activities. against MCF-7 human breast cancer cells.

Taking together, there is no doubt that black bean may process a significant anti-breast cancer property and can be considered as a functional food for reduced risk and treatment of breast cancer.


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Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Inhibition of Caco-2 colon, MCF-7 and Hs578T breast, and DU 145 prostatic cancer cell proliferation by water-soluble black bean condensed tannins by Bawadi HA1, Bansode RR, Trappey A 2nd, Truax RE, Losso JN.(PubMed)
(2) Fermentation product of soybean, black bean, and green bean mixture induces apoptosis in a wide variety of cancer cells by Chia JS1, Du JL, Wu MS, Hsu WB, Chiang CP, Sun A, Lu JJ, Wang WB.(PubMed)
(3) Phytochemicals of black bean seed coats: isolation, structure elucidation, and their antiproliferative and antioxidative activities by Dong M1, He X, Liu RH.(PubMed)