Kidney bean, the Best Anti-cancer Healthy Whole Food

Kidney bean may have potential effects against irregular cell growth in the body, causing various types of cancer, a recent study proposed.

Kidney bean is popular food, with kidney shape, strong flavor and color in reddish-brown in nature used often as an excellent dietary selection because of enormous health benefits with a good source of protein and minerals.

Cancer, a group of diseases characterized by cells growing and multiplying disordered and uncontrollable in our body. At the late stage, cancer cells may travel a distance away from the original site to invade other tissues and organs.

According to the joint study led by the Shenzhen University, chemical compound 60-kDa glucosamine binding lectin, white kidney bean lectin (WKBL), showed efficacy in inhibited HepG2 activity in compared to MCF7 cells through induced anti-proliferative and anti-apoptotic activities.

The study also found that epithelial tumor cell lines ( HONE-1) also are inhibited by chemical compound lectin in the activation of various extrinsic apoptosis pathway involved cell death.


Dr. Chan YS, the lead author said, " The (anti-proliferative) activity could be reduced by the addition of glucosamine, which occupies the binding sites of WKBL, indicating that carbohydrate-binding is crucial for the activity".

Beside chemical compound 60-kDa glucosamine binding lectin, 64-kDa glucosamine-specific lectin isolated from brown kidney bean also exhibited antiproliferative activity against numbers of cell lines including human breast cancer (MCF7) cells, hepatoma (HepG2) cells and nasopharyngeal carcinoma (CNE1 and CNE2) cells with concentration of an inhibitor of 5.12 µM, 32.85 µM, 3.12 µM and 40.12 µM respectively after treatment for 24 hours.

Particularly in breast cancer cell line MCF7, the formation of apoptotic bodies of the tumors is associated to apoptosis involved estrogen receptor(ER) stress and directed protein response.


Taking together, Kidney bean processed anti-cancer effects by exhibited anti-proliferative and anti-apoptotic activities against the early stage of development and progression of cancer in the various pathways. Please note that raw kidney beans are toxic.


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Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) White kidney bean lectin exerts anti-proliferative and apoptotic effects on cancercells by Chan YS1, Xia L2, Ng TB3.(PubMed)
(2) Isolation of a glucosamine binding leguminous lectin with mitogenic activity towards splenocytes and anti-proliferative activity towards tumor cells by Chan YS1, Wong JH, Fang EF, Pan W, Ng TB.(PubMed)