Body mass index, tumor characteristics, and prognosis following diagnosis of early-stage breast cancer

Posted by Chantel M. Research contributed by the US National Library of Medicine National Institutes of Health

The prevalence of childbearing age obesity is wide spreading in US, approximately, 50% of them are either overweight [body mass index (BMI) 25-29.9 kg/m(2)] or obese (BMI ≥ 30 kg/m(2)).
Body mass index, tumor characteristics, and prognosis following diagnosis of early-stage breast cancer
Many studies suggest increased body mass index (BMI) is associated with worse breast cancer outcomes. In the study to examine the association between BMI and risk of breast cancer recurrence, breast cancer-specific mortality, and all-cause mortality, and to evaluate whether tumor characteristics differ by BMI among a mammographically screened population with access to treatment, posted in PubMed, found that the growing evidence that obesity may contribute to poorer breast cancer outcomes, and also suggest that increased tumor proliferation among obese women is a pathway that explains part of their excess risk of adverse outcomes. 


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