Gene GYS2 as a novel genetic factor for polycystic ovary syndrome through obesity-related condition

 Posted by Chantel M. Research contributed by the US National Library of Medicine National Institutes of Health

The prevalence of childbearing age obesity is wide spreading in US, approximately, 50% of them are either overweight [body mass index (BMI) 25-29.9 kg/m(2)] or obese (BMI ≥ 30 kg/m(2)).
Gene GYS2 as a novel genetic factor for polycystic ovary syndrome through obesity-related condition
In a genome-wide association study to  investigate the role of genetic predisposition in the pathogenesis of polycystic ovary syndrome (PCOS) in relation to obesity in Koreans (n=1741), by the Osong Health Technology Administration complex, Chungcheongbuk-do, posted in PubMed, showed that there is a significant associations of GYS2 for body mass index in the discovery stage. The study provides a preliminary framework upon diverse genetic effects underlying PCOS in Korean women.

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