Skeletal benefits of soy isoflavones

Posted by Chantel Martiromo,  research contributed by PubMed

Osteoporosis is a worldwide problem of immense magnitude that is expected to worsen in many countries with aging populations. Consequently, there is a need to identify ways to reduce the risk of developing this disease. Accoding to the study by the Loma Linda University, posted in PubMed, fifteen clinical trials were identified that examined the effects of isoflavones or isoflavone-rich soy protein on bone mineral density.  Most trials were conducted for 1 year or less and involved relatively few (<30) participants per group. isoflavones reduce bone loss in younger postmenopausal women. These studies are inconsistent but generally suggest that isoflavones reduce bone loss in younger postmenopausal women. Similarly, the limited epidemiologic data generally show that among Asian populations isoflavone intake is associated with higher bone mineral density. The clinical data suggest that approximately 80 mg/day isoflavones are needed to derive skeletal benefits whereas the epidemiologic data suggest lower amounts are efficacious

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